Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Oct;67(10):743-745.
doi: 10.46747/cfp.6710743.

Bupropion for smoking cessation in adolescents

Bupropion for smoking cessation in adolescents

Tyler Yan et al. Can Fam Physician. 2021 Oct.

Abstract

Question: An adolescent who smokes regularly came to my clinic for help quitting. While I am aware that bupropion is a first-line medication for smoking cessation among adults, is it effective and safe for adolescents?

Answer: Most adolescent smokers in Canada would like to quit, but more than 90% of the attempts are unsuccessful. Bupropion appears to be more effective than other pharmacologic options in improving abstinence among adolescents who smoke in the short term; however, it is not approved by Health Canada for those younger than 18 years. Bupropion has not been associated with an increase in adverse events in smoking cessation trials. More research is needed on the long-term effectiveness and safety of bupropion in this population.

PubMed Disclaimer

Comment in

  • Environmental effect of smoking cessation.
    Green S, Davis M. Green S, et al. Can Fam Physician. 2021 Dec;67(12):882-883. doi: 10.46747/cfp.6712882_1. Can Fam Physician. 2021. PMID: 34906929 Free PMC article. No abstract available.

References

    1. National Centre for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health . The health consequences of smoking—50 years of progress: a report of the Surgeon General. Atlanta, GA: Centers for Disease Control and Prevention (US); 2014. - PubMed
    1. Jha P, Ramasundarahettige C, Landsman V, Rostron B, Thun M, Anderson RN, et al. . 21st-century hazards of smoking and benefits of cessation in the United States. N Engl J Med 2013;368(4):341-50. - PubMed
    1. Reid JL, Hammond D, Tariq U, Burkhalter R, Rynard VL, Douglas O.. Tobacco use in Canada: patterns and trends, 2019 edition. Waterloo, ON: Propel Centre for Population Health Impact, University of Waterloo; 2019.
    1. Connor Gorber S, Schofield-Hurwitz S, Hardt J, Levasseur G, Tremblay M.. The accuracy of self-reported smoking: a systematic review of the relationship between self-reported and cotinine-assessed smoking status. Nicotine Tob Res 2009;11(1):12-24. Epub 2009 Jan 27. - PubMed
    1. Cerdá M, Sarvet AL, Wall M, Feng T, Keyes KM, Galea S, et al. . Medical marijuana laws and adolescent use of marijuana and other substances: alcohol, cigarettes, prescription drugs, and other illicit drugs. Drug Alcohol Depend 2018;183:62-8. Epub 2017 Dec 7. - PMC - PubMed