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Comment
. 2021 Nov 1;35(11):e437-e438.
doi: 10.1097/BOT.0000000000002223.

In Response

Affiliations
Comment

In Response

Anthony R Carlini et al. J Orthop Trauma. .
No abstract available

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Conflict of interest statement

The authors report no conflict of interest.

Comment on

References

    1. Qadir R, Costales T, Coale M, et al. Vancomycin powder use in fractures at high risk of surgical site infection. J Orthop Trauma. 2021;35:23–28.
    1. Stafford RS. Regulating off-label drug use—rethinking the role of the FDA. N Engl J Med. 2008;358:1427–1429.
    1. OʼToole RV, Joshi M, Carlini AR, et al. Local antibiotic therapy to reduce infection after operative treatment of fractures at high risk of infection: a multicenter, randomized, controlled trial (VANCO study). J Orthop Trauma. 2017;31:S18–S24.
    1. Major Extremity Trauma Research Consortium (METRC). Effect of intrawound vancomycin powder in operatively treated high-risk tibia fractures: a randomized clinical trial. JAMA Surg.2021:e207259.
    1. Qadir R, Costales T, Coale M, et al. Topical vancomycin powder decreases the proportion of Staphylococcus aureus found in culture of surgical site infections in operatively treated fractures. J Orthop Trauma. 2021;35:17–22.

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