Pulmonary involvement in Sweet's syndrome (acute febrile neutrophilic dermatosis). Preleukemic and leukemic phases of acute myelogenous leukemia

Abstract

A 60-year-old man developed histologic lesions characteristic of acute febrile neutrophilic dermatosis in skin and lung during preleukemic and leukemic phases of acute myeloid leukemia. These lesions showed improvement and resolution during oral prednisone therapy, requiring higher doses during each relapse. The response to prednisone therapy was enhanced by concomitant administration of effective antileukemic chemotherapy.