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. 2021 Nov;42(11):940-942.
doi: 10.1016/j.it.2021.09.011. Epub 2021 Oct 13.

The meningeal lymphatics: regulators of Aβ immunotherapy?

Collin Laaker  1 , Zsuzsanna Fabry  2
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The meningeal lymphatics: regulators of Aβ immunotherapy?

Collin Laaker et al. Trends Immunol. 2021 Nov.

Abstract

A new study by Da Mesquita et al. reports on how meningeal lymphatic modulation may influence amyloid-beta immunotherapy and microglial function in mouse models of Alzheimer's disease (AD). This research has broad implications for unraveling the role meningeal lymphatics may play in regulating immunity in the brain during AD pathology and treatment.

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Conflict of interest statement

Declaration of interests The authors declare no conflicts of interest.

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