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Case Reports
. 2022 Jun;32(6):988-992.
doi: 10.1017/S1047951121004352. Epub 2021 Oct 18.

SARS-CoV-2 infection induced thyroid storm and heart failure in an adolescent girl

Bibhuti B Das  1 , Divya Shakti  1 , Jyothsna Akam-Venkata  1 , Obiageli Obi  2 , Michael D Weiland  1 , William Moskowitz  1
Affiliations
Case Reports

SARS-CoV-2 infection induced thyroid storm and heart failure in an adolescent girl

Bibhuti B Das et al. Cardiol Young. 2022 Jun.

Abstract

We report a case of thyroid storm precipitated by SARS-CoV-2 infection in an adolescent girl with a history of Graves disease and dilated cardiomyopathy. This case highlights that SARS-CoV-2 infection can potentially trigger a thyrotoxicosis crisis and acute decompensated heart failure in a patient with underlying thyroid disease and myocardial dysfunction even in the absence of multi-system inflammatory syndrome in children. We systematically reviewed the thyrotoxicosis cases with SARS-CoV-2 infection and described its impact on pre-existing dilated cardiomyopathy.

Keywords: SARS-CoV-2 infection in children; dilated cardiomyopathy; graves disease; thyroid storm.

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Figures

Figure 1.
Figure 1.
Chest X-Ray showing cardiomegaly and interstitial oedema.
Figure 2.
Figure 2.
M-mode images displaying left ventricular dimension and function.
Figure 3.
Figure 3.
ECG showing sinus tachycardia and non-specific ST changes.
Figure 4.
Figure 4.
Cardiac magnetic resonance imaging showing myocardial fibrosis on T1 mapping.
See this image and copyright information in PMC

References

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Supplementary concepts