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Case Reports
. 2022 Feb 1;47(2):e165-e166.
doi: 10.1097/RLU.0000000000003929.

Intracavernous Schwannoma Characterized With 18F-FDG, 68Ga-DOTATOC, and 18F-Choline PET

Affiliations
Case Reports

Intracavernous Schwannoma Characterized With 18F-FDG, 68Ga-DOTATOC, and 18F-Choline PET

Julien Farce et al. Clin Nucl Med. .

Abstract

We report the case of a 75-year-old man with history of prostate cancer whose left intracavernous lesion was successfully characterized by 3 PETs performed successively with different tracers. This poorly characterized tumor was initially discovered on an MRI conducted to investigate an acute diplopia and slowly growing during follow-up. On 18F-FDG PET, the lesion showed no significant uptake, and no extracranial lesion was found nor did it have increased 68Ga-DOTATOC uptake. Finally, this tumor displayed a high 18F-choline uptake, and no extracranial lesion was revealed with this tracer. The diagnosis of schwannoma without malignancy criterion was proven by biopsy.

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Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

References

    1. Munawar K, Nayak G, Fatterpekar GM, et al. Cavernous sinus lesions. Clin Imaging . 2020;68:71–89.
    1. Bolat S, Berding G, Dengler R, et al. Fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in the diagnosis of neurosarcoidosis. J Neurol Sci . 2009;287:257–259.
    1. Henze M, Schuhmacher J, Hipp P, et al. PET imaging of somatostatin receptors using [ 68 GA]DOTA-D-Phe1-Tyr3-octreotide: first results in patients with meningiomas. J Nucl Med . 2001;42:1053–1056.
    1. Dewey BJ, Howe BM, Spinner RJ, et al. FDG PET/CT and MRI features of pathologically proven schwannomas. Clin Nucl Med . 2021;46:289–296.
    1. De Waele M, Carp L, Lauwers P, et al. Paravertebral schwannoma with high uptake of fluorodeoxyglucose on positron emission tomography. Acta Chir Belg . 2005;105:537–538.

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