Parry-Romberg Syndrome

Excerpt

Parry Romberg syndrome (PRS), also referred to as progressive hemifacial atrophy, progressive facial hemiatrophy, or idiopathic hemifacial atrophy, was first described by C Parry and M Romberg. It is an idiopathic, gradually progressive craniofacial asymmetry, following the atrophy of subcutaneous tissue, muscles, osseous, and cartilaginous structures. It manifests in the first 2 decades in morphologically normal-born individuals. It commonly affects 1 or more dermatomes in the trigeminal nerve territory. It has an early onset of ophthalmic and neurological involvement and a variable maxillo-facial or cardiac involvement.