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Case Reports
. 2021 Oct 18;21(1):701.
doi: 10.1186/s12884-021-04179-5.

A very preterm infant born to mother of mirror syndrome secondary to fetomaternal hemorrhage: a case report

Sijie Song  1 , Yefang Zhu  1 , Gerhard Jorch  1   2 , Xiaoting Zhang  1 , Yan Wu  1 , Wen Chen  1 , Hua Gong  1 , Ligang Zhou  1 , Xueyan Wang  3 , Xiaoyun Zhong  4
Affiliations
Case Reports

A very preterm infant born to mother of mirror syndrome secondary to fetomaternal hemorrhage: a case report

Sijie Song et al. BMC Pregnancy Childbirth. .

Abstract

Background: Mirror syndrome (MS) is defined as maternal edema with fetal hydrops and placental edema with different etiologies, such as rhesus isoimmunization and twin-twin transfusion syndrome. Herein, we showcased a unique MS case secondary to fetomaternal hemorrhage (FMH).

Case presentation: A 32-year-old gravida 2 para 0 woman diagnosed with fetal hydrops was admitted to our hospital. Maternal laboratory tests revealed anemia, slightly increased creatinine and uric acid levels, hypoproteinemia, and significantly increased alpha-fetoprotein and hemoglobin-F levels. Therefore, FMH was diagnosed initially. Two days after admission, the woman had unexpectedly progressive anasarca and started to feel chest distress, palpitations, lethargy, and oliguria, and MS was suspected. An emergency cesarean section was performed to terminate the pregnancy. The maternal clinical symptoms and laboratory tests rapidly improved after delivery. A very preterm infant with a 2080-g birthweight at 31 weeks gestation survived after emergency cesarean section, active resuscitation, emergency blood transfusion, abdominocentesis, and advanced life support.

Conclusions: FMH could develop into MS, providing new insights into the etiology of MS. Once MS is diagnosed, emergency cesarean section might be an alternative treatment. The very preterm infant survived with a favorable long-term outcome, and a well-trained perinatal work team is needed for such cases.

Keywords: Etiology; Fetomaternal hemorrhage; Mirror syndrome; Outcome; Very preterm infant.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
The edema/ascites and rescue process of the infant in the NICU
See this image and copyright information in PMC

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