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. 2021 Oct 19;21(1):1884.
doi: 10.1186/s12889-021-11868-5.

Relative children's lipid accumulation with hypertension in Chinese children and adolescents

Zizhe Zhang  1 , Li Zhang  1 , Lili Sun  1 , Bangxuan Wang  1 , Yongting Yuan  1 , Huaiquan Gao  2 , Lianguo Fu  3
Affiliations

Relative children's lipid accumulation with hypertension in Chinese children and adolescents

Zizhe Zhang et al. BMC Public Health. .

Abstract

Background: This study aimed to develop a novel indicator associated with hypertension in Chinese children and adolescents, the relative children's lipid accumulation product (RCLAP).

Methods: A cross-sectional study was conducted in 2018. A total of 683 students aged 8-15 years were recruited via a stratified cluster sampling Methods. Anthropometric indexes (waist circumference (WC), Body mass index (BMI), Waist-height ratio (WHtR), logarithm children LAP (LnCLAP), RCLAP per height (RCLAP-H)) were standardized using a z-score method (standardized variables: SWC, SBMI, SWHtR, SLnCLAP, SRCLAP-H). A logistic regression model was performed to evaluate the association of the above indicators with the outcome of hypertension.

Results: The overall prevalence of hypertension was 5.7% (5.5% in boys, 6.0% in girls). SWC ≥ P75, SBMI ≥ P75, SWHtR ≥ P75, SlnCLAP ≥ P75 and SRCLAP-H ≥ P75 significantly increased risk of hypertension, with odds ratios (OR) of 2.21 (95% confidence interval (CI): 1.13, 4.30), 2.30 (1.18, 4.49), 2.64 (1.35, 5.14), 4.43 (2.28, 8.61), and 4.49 (2.31, 8.71), respectively.

Conclusion: RCLAP is a novel indicator associated with hypertension in Chinese children and adolescents, and it performs better than WC, BMI, WHtR and children LAP.

Keywords: Children and adolescents; Hypertension; children’s lipid accumulation product.

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Conflict of interest statement

The authors declare that they have no competing interests.

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