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. 2022 Jan 1;205(1):126-129.
doi: 10.1164/rccm.202108-1903LE.

Decreased Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome

Esther de Boer  1   2 , Irina Petrache  1   2 , Nir M Goldstein  1 , J Tod Olin  1 , Rebecca C Keith  1   2 , Brian Modena  1 , Michael P Mohning  1   2 , Zulma X Yunt  1   2 , Inigo San-Millán  2   3 , Jeffrey J Swigris  1   2
Affiliations

Decreased Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome

Esther de Boer et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
(A and B) Blood lactate and (C and D) fat oxidation rate as a function of power output, measured in Watts (W) during graded exercise in patients with PASC with and without comorbidities compared with a historic cohort (data obtained from Reference 3) of patients with metabolic syndrome and moderately active individuals. No comorbidities (n = 27); comorbidities (n = 23). Mean ± SEM; one-way ANOVA P < 0.0001 (Welch or Brown-Forsythe); Dunnett’s multiple comparison test: *P < 0.05, ***P < 0.001, and ****P < 0.0001. PASC = post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
See this image and copyright information in PMC

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