Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov-Dec;20(6):706-715.
doi: 10.1080/15402002.2021.1992408. Epub 2021 Oct 19.

Nighttime Waking to Smoke, Stress, and Nicotine Addiction

Affiliations

Nighttime Waking to Smoke, Stress, and Nicotine Addiction

Steven A Branstetter et al. Behav Sleep Med. 2022 Nov-Dec.

Abstract

Introduction: Up to one-half of cigarette smokers may wake up during the night and smoke. This behavior may result in greater likelihood of cessation failure, clinically relevant sleep difficulties, and a range of health issues. Whereas the scientific literature has often attributed this behavior to nicotine dependence, up to 85% of smokers who wake at night and smoke attribute this behavior to factors other than nicotine. This study examines the relations between nicotine dependence, psychological distress, perceived stress, and waking at night to smoke.

Methods: A total of 351 adult smokers from the Pennsylvania Adult Smoking Study (PASS) completed self-report surveys and provided saliva for the evaluation of cotinine values. Survey instruments included measures of nicotine addiction, perceived stress, a broad measure of global psychological distress, and a range of demographic factors.

Results: Logistic regression demonstrated that nicotine addiction, psychological distress, and perceived stress were all related to waking at night to smoke, but cotinine levels were not. Mediation models found that psychological distress had a direct relation to waking at night to smoke, even when considering nicotine addiction and other causes of sleep disturbances (e.g., apnea and chronic physical pain). Alternative moderation and mediation models were conducted but did not support other plausible associations between variables.

Conclusions: Waking at night to smoke is likely the result of both nicotine dependence and psychological distress. Given that cotinine levels were not associated with waking at night, the mechanisms of how nicotine dependence may affect waking at night need further investigation.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
Mediation model of psychological distress and waking to smoke
Figure 2:
Figure 2:
Alternate moderated mediation model

References

    1. Alsaadi SM, McAuley JH, Hush JM, & Maher CG (2011). Prevalence of sleep disturbance in patients with low back pain. European Spine Journal, 20(5), 737–743. 10.1007/s00586-010-1661-x - DOI - PMC - PubMed
    1. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). 10.1176/appi.books.9780890425596 - DOI
    1. Benjamini Y, & Hochberg Y (1995). Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing. Journal of the Royal Statistical Society. Series B (Methodological), 57(1), 289–300. 10.2307/2346101 - DOI
    1. Bover MT, Foulds J, Steinberg MB, Richardson D, & Marcella SW (2008). Waking at night to smoke as a marker for tobacco dependence: patient characteristics and relationship to treatment outcome. International Journal of Clinical Practice, 62(2), 182–190. 10.1111/j.1742-1241.2007.01653.x - DOI - PubMed
    1. Branstetter SA, Horton WJ, Mercincavage M, & Buxton OM (2016). Severity of Nicotine Addiction and Disruptions in Sleep Mediated by Early Awakenings. Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco, 18(12), 2252–2259. 10.1093/ntr/ntw179 - DOI - PubMed

Publication types