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Editorial
. 2021 Oct 19;60(Suppl 4):iv1-iv3.
doi: 10.1093/rheumatology/keab461.

Interleukin-23 in perspective

Jonathan P Sherlock  1   2 , Daniel J Cua  1
Affiliations
Editorial

Interleukin-23 in perspective

Jonathan P Sherlock et al. Rheumatology (Oxford). .
No abstract available

Keywords: IL-23p19-specific inhibitors; biologic; biologic therapy; cytokines; interleukin-23; psoriasis; psoriatic; psoriatic arthritis; psoriatic disease; tumour necrosis factor inhibitors.

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References

    1. Oppmann B, Lesley R, Blom B. et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000;13:715–25. - PubMed
    1. Sherlock JP, Zúñiga LA, Cua DJ.. IL-23 in health and disease. In: Yoshimoto T, Yoshimoto T, eds. Cytokine frontiers: regulation of immune responses in health and disease. Tokyo: Springer, 2014:179–98.
    1. Cua DJ, Sherlock J, Chen Y. et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003;421:744–8. - PubMed
    1. Langrish CL, McKenzie BS, Wilson NJ. et al. IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol Rev 2004;202:96–105. - PubMed
    1. Matusevicius D, Kivisäkk P, He B. et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999;5:101–4. - PubMed

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