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. 2021 Oct;155 Suppl 1(Suppl 1):28-44.
doi: 10.1002/ijgo.13865.

Cancer of the cervix uteri: 2021 update

Neerja Bhatla  1 , Daisuke Aoki  2 , Daya Nand Sharma  3 , Rengaswamy Sankaranarayanan  4
Affiliations

Cancer of the cervix uteri: 2021 update

Neerja Bhatla et al. Int J Gynaecol Obstet. 2021 Oct.

Abstract

Since the publication of the 2018 FIGO Cancer Report, giant strides have been made in the global effort to reduce the burden of cervical cancer, with the World Health Organization (WHO) rolling out a global strategy for cervical cancer elimination, aiming for implementation by 2030. In over 130 countries, including low- and middle-income countries, HPV vaccination is now included in the national program. Screening has seen major advances with wider implementation of HPV testing. These interventions will take a few years to show their impact. Meanwhile, over half a million new cases are added each year. FIGO's revised staging of cervical cancer (2018) has been widely implemented and retrospective analyses of data based on the new staging have been published. Minimally invasive surgery has been shown to be disadvantageous in women with cervical cancer. This chapter discusses the management of cervical cancer based on the stage of disease, including attention to palliation and quality of life issues.

Keywords: FIGO Cancer Report; HPV vaccination; cancer; cervix; radiation; screening; staging; surgery.

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Conflict of interest statement

Outside of the submitted work, NB has received research funding through her institute from MSD, GlaxoSmithKline, and Digene/Qiagen Inc. Outside of the submitted work, DA has received honoraria from AstraZeneca, Chugai Pharmaceutical Co. Ltd., Eisai Co. Ltd, Taiho Pharmaceutical Co. Ltd, Coviden Japan Inc, Johnson & Johnson, and Takeda Pharmaceutical Co. Ltd; consulting fees from Takeda Pharmaceutical Co. Ltd, AstraZeneca, MSD, and Chugai Pharmaceutical Co. Ltd; and holds unpaid positions with the Asian Society of Gynecologic Oncology, Japan Society of Gynecologic Oncology, and the Japan Society of Obstetrics and Gynecology. RS advises on cancer prevention and early detection for Karkinos Healthcare Private Limited, a managed healthcare company in India. DNS has no conflicts of interest to declare.

Figures

FIGURE 1
FIGURE 1
CT scan images showing radiotherapy planning using: (a) conventional four‐field box technique; and (b) intensity modulated radiation therapy (IMRT) planning. Normal tissues such as bladder and bowel are relatively spared in IMRT planning
FIGURE 2
FIGURE 2
Interstitial brachytherapy implant: (a) clinical image of a patient showing the perineal template and the steel needles; (b) CT scan image showing the brachytherapy needles inserted into the pelvis
See this image and copyright information in PMC

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MeSH terms