Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Dec:113:341-343.
doi: 10.1016/j.ijid.2021.10.025. Epub 2021 Oct 17.

Sudden sensorineural hearing loss after COVID-19 vaccination

Affiliations
Case Reports

Sudden sensorineural hearing loss after COVID-19 vaccination

Junhui Jeong et al. Int J Infect Dis. 2021 Dec.

Abstract

Coronavirus disease 2019 (COVID-19) spread rapidly and was declared a pandemic. In this situation, vaccination for COVID-19 is important and has been prompted in many countries. Rare serious adverse events including Guillain-Barré syndrome, thrombosis with thrombocytopenia syndrome, and myocarditis after COVID-19 vaccinations have been reported. Otolaryngologic adverse events after COVID-19 vaccination were reported, including several cases of sudden sensorineural hearing loss (SSNHL). We report three patients with SSNHL within three days after COVID-19 vaccination and consider an association between them. Although there is no evidence of an association between vaccination and SSNHL, the adverse event of SSNHL after COVID-19 vaccination should be kept in mind because viral infection could be the etiology of SSNHL, which is an otologic emergency that requires prompt treatment with steroids.

Keywords: COVID-19; COVID-19 vaccine; SARS-CoV-2; Sudden sensorineural hearing loss; vaccination; vaccine.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Figure 1
Figure 1
Initial hearing threshold with weighted four-frequency average ([500 Hz + 1000 Hz × 2 + 2000 Hz × 2 + 4000 Hz] / 6) on pure tone audiometry after coronavirus disease 2019 vaccination. (A) In a 64-year-old female with right sudden sensorineural hearing loss after the first dose of Oxford-AstraZeneca, it was 86 dB in the right and 17 dB in the left ear. (B) In a 42-year-old male with left acute low-frequency hearing loss after the first dose of Pfizer-BioNTech, it was 13 dB in the right and 9 dB in the left ear, but there was acute hearing loss at low frequencies in the left ear (40, 45, and 30 dB at 125, 250, and 500 Hz, respectively). (C) In an 18-year-old male with right sudden sensorineural hearing loss after the second dose of Pfizer-BioNTech, it was 89 dB in the right and 13 dB in the left ear.

References

    1. Baxter R, Lewis N, Bohrer P, Harrington T, Aukes L, Klein NP. Sudden-onset sensorineural hearing loss after immunization: a case-centered analysis. Otolaryngol Head Neck Surg. 2016;155(1):81–86. - PMC - PubMed
    1. Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, et al. Clinical practice guideline: sudden hearing loss (Update) Otolaryngol Head Neck Surg. 2019;161(1_suppl):S1–45. - PubMed
    1. De Marco F, De Cesare DP, Di Folco F, Massoni F, Tomei G, Di Luca NM, et al. Post vaccinal temporary sensorineural hearing loss. Int J Environ Res Public Health. 2018;15(8):1780. - PMC - PubMed
    1. Formeister EJ, Chien W, Agrawal Y, Carey JP, Stewart CM, Sun DQ. Preliminary analysis of association between COVID-19 vaccination and sudden hearing loss using US centers for disease control and prevention vaccine adverse events reporting system data. JAMA Otolaryngol Head Neck Surg. 2021;147(7):674–676. - PMC - PubMed
    1. Güçlü O, Dereköy FS. Sudden hearing loss after rabies vaccination. Balkan Med J. 2013;30(3):327–328. - PMC - PubMed

Publication types

Substances