Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Oct 20;16(1):311.
doi: 10.1186/s13019-021-01696-4.

Clinical application of pulmonary vascular resistance in patients with pulmonary arterial hypertension

Affiliations
Review

Clinical application of pulmonary vascular resistance in patients with pulmonary arterial hypertension

Jianying Deng. J Cardiothorac Surg. .

Abstract

Pulmonary arterial hypertension is a type of malignant pulmonary vascular disease, which is mainly caused by the increase of pulmonary vascular resistance due to the pathological changes of the pulmonary arteriole itself, which eventually leads to right heart failure and death. As one of the diagnostic indicators of hemodynamics, pulmonary vascular resistance plays an irreplaceable role in the pathophysiology, diagnosis and treatment of pulmonary arterial hypertension. It provides more references for the evaluation of pulmonary arterial hypertension patients. This article summarizes the clinical application of pulmonary vascular resistance in patients with pulmonary arterial hypertension.

Keywords: Pulmonary arterial hypertension; Pulmonary circulation; Pulmonary vascular resistance.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there are no competing interests.

References

    1. Galiè N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, et al. 2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: the joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) Eur Heart J. 2016;37(1):67–119. doi: 10.1093/eurheartj/ehv317. - DOI - PubMed
    1. A.E. Lammers, C. Apitz, P. Zartner, A. Hager, K.O. Dubowy, G. Hansmann, Diagnostics, monitoring and outpatient care in children with suspected pulmonary hypertension/paediatric pulmonary hypertensive vascular disease. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK, Heart 102 (2016) Suppl 2:ii1–13. - PubMed
    1. Clark A, Tawha M. Pulmonary vascular dynamics. Compr Physiol. 2019;9(3):1081–1100. doi: 10.1002/cphy.c180033. - DOI - PubMed
    1. Shimoda LA. Overview: pulmonary vascular function in health and disease. J Physiol. 2019;597(4):973–974. doi: 10.1113/JP277375. - DOI - PMC - PubMed
    1. Brittain EL, Thennapan T, Maron BA, Chan SY, Austin ED, Spiekerkoetter E, et al. Update in pulmonary vascular disease 2016 and 2017. Am J Respir Crit Care Med. 2018;198(1):13–23. doi: 10.1164/rccm.201801-0062UP. - DOI - PMC - PubMed