Bacterial defense islands limit viral attack

Sean Meaden^{1

2}, Peter C Fineran^{2

3

4

5}

Affiliations

¹ Biosciences, University of Exeter, Penryn, UK.
² Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
³ Bioprotection Aotearoa, University of Otago, Dunedin, New Zealand.
⁴ GeneticsOtago, University of Otago, Dunedin, New Zealand.
⁵ Maurice Wilkins Centre for Molecular Biodiscovery, University of Otago, Dunedin, New Zealand.

Comment

Sean Meaden et al. Science. 2021.

. 2021 Oct 22;374(6566):399-400.

doi: 10.1126/science.abm2444. Epub 2021 Oct 21.

Sean Meaden^{1

2}, Peter C Fineran^{2

3

4

5}

¹ Biosciences, University of Exeter, Penryn, UK.
² Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
³ Bioprotection Aotearoa, University of Otago, Dunedin, New Zealand.
⁴ GeneticsOtago, University of Otago, Dunedin, New Zealand.
⁵ Maurice Wilkins Centre for Molecular Biodiscovery, University of Otago, Dunedin, New Zealand.

Abstract

Mobile phage-defense genes underpin rapid evolution of resistance in nature.

Rapid evolutionary turnover of mobile genetic elements drives bacterial resistance to phages.
Hussain FA, Dubert J, Elsherbini J, Murphy M, VanInsberghe D, Arevalo P, Kauffman K, Rodino-Janeiro BK, Gavin H, Gomez A, Lopatina A, Le Roux F, Polz MF. Hussain FA, et al. Science. 2021 Oct 22;374(6566):488-492. doi: 10.1126/science.abb1083. Epub 2021 Oct 21. Science. 2021. PMID: 34672730