Reducing Ventilator-associated Brain Injury by Diaphragm Neurostimulation: Racking the Diaphragm to Protect the Brain?

Martin Dres^{1

2}, Gianluigi Li Bassi^{3

4

5

6}

Affiliations

¹ Sorbonne Université UMRS_1158 Neurophysiologie Respiratoire Expérimentale et Clinique Paris, France.
² Sorbonne Université Hôpital Pitié-Salpêtrière Paris, France.
³ Critical Care Research Group The Prince Charles Hospital Chermside, Queensland, Australia.
⁴ The University of Queensland Brisbane, Queensland, Australia.
⁵ Intensive Care Unit St Andrew's War Memorial Hospital Spring Hill, Queensland, Australia.
⁶ Intensive Care Unit The Wesley Hospital Auchenflower, Queensland, Australia.

Editorial

Martin Dres et al. Am J Respir Crit Care Med. 2021.

. 2021 Dec 15;204(12):1355-1357.

doi: 10.1164/rccm.202110-2312ED.

Martin Dres^{1

2}, Gianluigi Li Bassi^{3

4

5

6}

¹ Sorbonne Université UMRS_1158 Neurophysiologie Respiratoire Expérimentale et Clinique Paris, France.
² Sorbonne Université Hôpital Pitié-Salpêtrière Paris, France.
³ Critical Care Research Group The Prince Charles Hospital Chermside, Queensland, Australia.
⁴ The University of Queensland Brisbane, Queensland, Australia.
⁵ Intensive Care Unit St Andrew's War Memorial Hospital Spring Hill, Queensland, Australia.
⁶ Intensive Care Unit The Wesley Hospital Auchenflower, Queensland, Australia.

No abstract available

Comment on

Transvenous Diaphragm Neurostimulation Mitigates Ventilation-associated Brain Injury.
Bassi TG, Rohrs EC, Fernandez KC, Ornowska M, Nicholas M, Gani M, Evans D, Reynolds SC. Bassi TG, et al. Am J Respir Crit Care Med. 2021 Dec 15;204(12):1391-1402. doi: 10.1164/rccm.202101-0076OC. Am J Respir Crit Care Med. 2021. PMID: 34491883 Free PMC article.

1. Slutsky AS, Ranieri VM. Ventilator-induced lung injury. N Engl J Med . 2014;370:980. - PubMed
1. Vassilakopoulos T, Petrof BJ. Ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med . 2004;169:336–341. - PubMed
1. Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE, Jr, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA . 2004;291:1753–1762. - PubMed
1. Hopkins RO, Weaver LK, Pope D, Orme JF, Bigler ED, Larson-LOHR V. Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med . 1999;160:50–56. - PubMed
1. Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, et al. Canadian Critical Care Trials Group. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med . 2011;364:1293–1304. - PubMed