Subcutaneous interferon beta-1a in COVID-19: raking the ashes of an intervention trial
- PMID: 34672951
- PMCID: PMC8523115
- DOI: 10.1016/S2213-2600(21)00412-4
Subcutaneous interferon beta-1a in COVID-19: raking the ashes of an intervention trial
Conflict of interest statement
TW reports being a founder and director of, and a shareholder in, my mhealth, outside of the submitted work; receiving research grants for trials of interferon beta and other COVID-19 treatments from AstraZeneca, GlaxoSmithKline, Synairgen, Bergenbio, UCB, NIHR, UKRI, and my mhealth within the submitted work; receiving consultancy fees from AstraZeneca, Synairgen, my mhealth, Valneva, OM Pharma, Boehringer Ingelheim, and Roche within the submitted work; receiving fees for attending lectures and meetings from Boehringer Ingelheim, AstraZeneca, Chiesi, Teva, and GlaxoSmithKline outside the submitted work; receiving travel support for attending conferences and meetings from Nutricia, AstraZeneca, Chiesi, Boehringer Ingelheim, and GlaxoSmithKline outside the submitted work; applying for patents for bacterial vaccines with GlaxoSmithKline and my mhealth, outside of the submitted work; being a member of a specialist chronic obstructive pulmonary disease advisory group within the submitted work; and being a member of the independent data monitoring committee of a vaccine study sponsored by Valneva and Synairgen within the submitted work.
Comment on
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Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial.Lancet Respir Med. 2021 Dec;9(12):1365-1376. doi: 10.1016/S2213-2600(21)00384-2. Epub 2021 Oct 18. Lancet Respir Med. 2021. PMID: 34672949 Free PMC article. Clinical Trial.
References
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- Khoury DS, Cromer D, Reynaldi A, et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat Med. 2021;27:1205–1211. - PubMed
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