Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Jan;84(2):429-33.
doi: 10.1073/pnas.84.2.429.

Lateral diffusion of lipids in complex biological membranes

T J O'Leary

Lateral diffusion of lipids in complex biological membranes

T J O'Leary. Proc Natl Acad Sci U S A. 1987 Jan.

Erratum in

  • Proc Natl Acad Sci U S A 1987 Aug;84(15):5231

Abstract

Lateral diffusion of lipids in biological membranes may be influenced by polypeptides, proteins, and other nonlipid membrane constituents. Using concepts from scaled-particle theory, we extend the free-volume model for lipid diffusion to membranes having an arbitrarily large number of components. This theory clarifies the interpretation of the free-volume theory, better reproduces the free-area dependence of lipid lateral diffusion rates, and quantitatively predicts the experimental observation that the lateral diffusion rates of membrane lipids are significantly reduced when proteins or polypeptides are incorporated in the membrane.

PubMed Disclaimer

References

    1. Nature. 1975 Sep 4;257(5521):28-32 - PubMed
    1. J Mol Biol. 1977 May 25;112(3):437-52 - PubMed
    1. Biopolymers. 1978 Sep;17(9):2285-8 - PubMed
    1. J Membr Biol. 1979 Jul 31;48(3):215-36 - PubMed
    1. Biochemistry. 1980 Dec 23;19(26):6044-50 - PubMed

LinkOut - more resources