The Trouble with CBD Oil
- PMID: 34676324
- PMCID: PMC8489347
- DOI: 10.1159/000489287
The Trouble with CBD Oil
Abstract
In just a few years, cannabidiol (CBD) has become immensely popular around the world. After initially being discovered as an effective self-medication for Dravet syndrome in children, CBD is now sold and used to treat a wide range of medical conditions and lifestyle diseases. The cannabinoid CBD, a non-psychoactive isomer of the more infamous tetrahydrocannabinol (THC), is available in a growing number of administration modes, but the most commonly known is CBD oil. There are currently dozens, if not hundreds, of producers and sellers of CBD oils active in the market, and their number is increasing rapidly. Those involved vary from individuals who prepare oils on a small scale for family and (Facebook) friends to compounding pharmacies, pharmaceutical companies, and licensed cannabis producers. Despite the growing availability of CBD, many uncertainties remain about the legality, quality, and safety of this new "miracle cure." As a result, CBD is under scrutiny on many levels, ranging from national health organizations and agricultural lobbyists to the WHO and FDA. The central question is whether CBD is simply a food supplement, an investigational new medicine, or even a narcotic. This overview paper looks into the known risks and issues related to the composition of CBD products, and makes recommendations for better regulatory control based on accurate labeling and more scientifically supported health claims. The intention of this paper is to create a better understanding of the benefits versus the risks of the current way CBD products are produced, used, and advertised.
Keywords: CBD oil; Cannabidiol; Cannabis; Composition; Contaminants; Quality; Regulatory status; Safety.
Copyright © 2018 by S. Karger AG, Basel.
Conflict of interest statement
The author has no conflicts of interest to declare. No funding was received for this study.
References
-
- Puri PS. Winterization of oils and fats. J Am Oil Chem Soc. 1980;57:A848–A850.
-
- Havelka J. What is CBG and what are the benefits of this cannabinoid? Leafly (Internet) 2017 https://www.leafly.com/news/cannabis-101/what-is-cbg-cannabinoid (Accessed April 13, 2018)
-
- Romano LL, Hazekamp A. Cannabis oil: chemical evaluation of an upcoming cannabis-based medicine. Cannabinoids. 2013;1:1–11.
-
- Sexton M, Shelton K, Haley P, West M. Evaluation of cannabinoid and terpenoid content: cannabis flower compared to supercritical CO2 concentrate. Planta Med. 2018;84:234–241. - PubMed
-
- Ross SA, ElSohly MA. The volatile oil composition of fresh and air-dried buds of Cannabis sativa. J Nat Prod. 1996;59:49–51. - PubMed
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