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. 2021 Oct 14;9(10):1371.
doi: 10.3390/healthcare9101371.

Microbiome Forensic Biobanking: A Step toward Microbial Profiling for Forensic Human Identification

Affiliations

Microbiome Forensic Biobanking: A Step toward Microbial Profiling for Forensic Human Identification

Luciana Caenazzo et al. Healthcare (Basel). .

Abstract

In recent years many studies have highlighted the great potential of microbial analysis in human identification for forensic purposes, with important differences in microbial community composition and function across different people and locations, showing a certain degree of uncertainty. Therefore, further studies are necessary to enable forensic scientists to evaluate the risk of microbial transfer and recovery from various items and to further critically evaluate the suitability of current human DNA recovery protocols for human microbial profiling for identification purposes. While the establishment and development of microbiome research biobanks for clinical applications is already very structured, the development of studies on the applicability of microbiome biobanks for forensic purposes is still in its infancy. The creation of large population microbiome biobanks, specifically dedicated to forensic human identification, could be worthwhile. This could also be useful to increase the practical applications of forensic microbiology for identification purposes, given that this type of evidence is currently absent from most real casework investigations and judicial proceedings in courts.

Keywords: biobank; forensic; human identification; microbiome.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Mandl K.D., Glauser T., Krantz I.D., Avillach P., Bartels A., Beggs A.H., Biswas S., Bourgeois F.T., Corsmo J., Dauber A., et al. Genomics Research and Innovation Network. The Genomics Research and Innovation Network: Creating an interoperable, federated, genomics learning system. Genet. Med. 2020;22:371–380. doi: 10.1038/s41436-019-0646-3. - DOI - PMC - PubMed
    1. Lewis C., McQuaid S., Hamilton P.W., Salto-Tellez M., McArt D., James J.A. Building a ‘Repository of Science’: The importance of integrating biobanks within molecular pathology programmes. Eur. J. Cancer. 2016;67:191–199. doi: 10.1016/j.ejca.2016.08.009. - DOI - PubMed
    1. Hartman V., Matzke L., Watson P.H. Biospecimen Complexity and the Evolution of Biobanks. Biopreserv. Biobank. 2019;17:264–270. doi: 10.1089/bio.2018.0120. - DOI - PubMed
    1. Coppola L., Cianflone A., Grimaldi A.M., Incoronato M., Bevilacqua P., Messina F., Baselice S., Soricelli A., Mirabelli P., Salvatore M. Biobanking in health care: Evolution and future directions. J. Transl. Med. 2019;17:172. doi: 10.1186/s12967-019-1922-3. - DOI - PMC - PubMed
    1. Sudlow C., Gallacher J., Allen N., Beral V., Burton P., Danesh J., Downey P., Elliott P., Green J., Landray M., et al. UK biobank: An open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 2015;12:e1001779. doi: 10.1371/journal.pmed.1001779. - DOI - PMC - PubMed