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. 2021 Oct 2;13(10):3493.
doi: 10.3390/nu13103493.

Feasibility and Efficiency of the BEFORE (Better Exercise and Food, Better Recovery) Prehabilitation Program

Thaís T T Tweed  1 , Misha A T Sier  1 , Ad A Van Bodegraven  2 , Noémi C Van Nie  1 , Walther M W H Sipers  3 , Evert-Jan G Boerma  1 , Jan H M B Stoot  1
Affiliations

Feasibility and Efficiency of the BEFORE (Better Exercise and Food, Better Recovery) Prehabilitation Program

Thaís T T Tweed et al. Nutrients. .

Abstract

Prehabilitation has been postulated as an effective preventive intervention to reduce postoperative complications, particularly for elderly patients with a relatively high risk of complications. To date, it remains to be determined whether prehabilitation increases physical capacity and reduces postoperative complications. The aim of this study was to assess the feasibility of a 4-week multimodal prehabilitation program consisting of a personalized, supervised training program and nutritional intervention with daily fresh protein-rich food for colorectal cancer patients aged over 64 years prior to surgery. The primary outcome was the feasibility of this prehabilitation program defined as ≥80% compliance with the exercise training program and nutritional intervention. The secondary outcomes were the organizational feasibility and acceptability of the prehabilitation program. A compliance rate of ≥80% to both the exercise and nutritional intervention was accomplished by 6 patients (66.7%). Attendance of ≥80% at all 12 training sessions was achieved by 7 patients (77.8%); all patients (100%) attended ≥80% of the available training sessions. Overall, compliance with the training was 91.7%. Six patients (66.7%) accomplished compliance of ≥80% with the nutritional program. The median protein intake was 1.2 (g/kg/d). No adverse events occurred. This multimodal prehabilitation program was feasible for the majority of patients.

Keywords: colorectal cancer; colorectal surgery; complications; enhanced recovery after surgery; feasibility; functional capacity; multimodal; prehabilitation.

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Conflict of interest statement

The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure A1
Figure A1
VAS score appetite (1st screening).
Figure A2
Figure A2
VAS score appetite (2nd screening).
Figure A3
Figure A3
VAS score food experience (2nd screening).
Figure 1
Figure 1
Consort diagram.
Figure 2
Figure 2
Handgrip strength (kg) before and after prehabilitation.
Figure 3
Figure 3
Maximum exercise capacity (Watt) before and after prehabilitation.
Figure 4
Figure 4
Maximum oxygen uptake (mL/kg/min) before and after prehabilitation.
Figure 5
Figure 5
Oxygen uptake at Ventilatory Anaerobic Threshold (VAT) before and after prehabilitation.
See this image and copyright information in PMC

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