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Comment
. 2021 Dec;9(12):1356-1358.
doi: 10.1016/S2213-2600(21)00458-6. Epub 2021 Oct 21.

Waning immunity to SARS-CoV-2: implications for vaccine booster strategies

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Comment

Waning immunity to SARS-CoV-2: implications for vaccine booster strategies

Daniel M Altmann et al. Lancet Respir Med. 2021 Dec.
No abstract available

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Conflict of interest statement

DMA and RJB receive support from the UK Medical Research Council (MR/S019553/1, MR/R02622X/1, MR/V036939/1, and MR/W020610/1) and the National Institute for Health Research (NIHR) Imperial Biomedical Research Centre Institute for Translational Medicine and Therapeutics; Cystic Fibrosis Trust Strategic Research Centre (2019SRC015); NIHR Efficacy and Mechanism Evaluation Fast Track (NIHR134607); NIHR Long Covid (COV-LT2-0027); Innovate UK (SBRI 10008614); and Horizon 2020 Marie Skłodowska-Curie Innovative Training Network European Training Network (no. 860325). Both authors are members of the Global T cell Expert Consortium and have consulted for Oxford Immunotec, outside of the submitted work.

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References

    1. Dolgin E. COVID vaccine immunity is waning — how much does that matter? Nature. 2021;597:606–607. - PubMed
    1. Milne G, Hames T, Scotton C, et al. Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity? Lancet Respir Med. 2021 doi: 10.1016/S2213-2600(21)00407-0. published online Oct 21. - DOI - PMC - PubMed
    1. The Irish Times Science uncertain about need for vaccine boosters, WHO says. Aug 18, 2021. https://www.irishtimes.com/news/health/science-uncertain-about-need-for-...
    1. Edridge AWD, Kaczorowska J, Hoste ACR, et al. Seasonal coronavirus protective immunity is short-lasting. Nat Med. 2020;26:1691–1693. - PubMed
    1. Reynolds CJ, Swadling L, Gibbons JM, et al. Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection. Sci Immunol. 2020;5 - PMC - PubMed

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