Adult-Onset Still's Disease in a 28-Year-Old Man From Ghana
- PMID: 34692336
- PMCID: PMC8528165
- DOI: 10.7759/cureus.18126
Adult-Onset Still's Disease in a 28-Year-Old Man From Ghana
Abstract
Adult-onset Still's disease is a rare, autoinflammatory disease characterized by spiking fevers, arthritis, salmon-colored skin rash, and leukocytosis. It has been compared to systemic juvenile idiopathic arthritis because of its similar features but is much rarer than its pediatric counterpart. It is usually treated with corticosteroids and disease-modifying anti-rheumatic drugs. However, those with refractory disease are candidates for one of many biological therapies. We present the case of a 28-year-old man who was successfully managed with first-line steroid therapy.
Keywords: adult onset still's disease (aosd); high ferritin; interleukin (il)-6; systemic juvenile idiopathic arthritis; yamaguchi.
Copyright © 2021, Kashfi et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
References
-
- Neurological manifestations of adult-onset Still's disease-case-based review. Santos M, Rodrigues D, Santos H, et al. Clin Rheumatol. 2021;40:407–411. - PubMed
-
- A comprehensive review on adult onset Still's disease. Giacomelli R, Ruscitti P, Shoenfeld Y. J Autoimmun. 2018;93:24–36. - PubMed
-
- Preliminary criteria for classification of adult Still's disease. Yamaguchi M, Ohta A, Tsunematsu T, et al. https://pubmed.ncbi.nlm.nih.gov/1578458/ J Rheumatol. 1992;19:424–430. - PubMed
Publication types
LinkOut - more resources
Full Text Sources