doi: 10.1111/j.1744-313x.1986.tb01101.x.
Loss of HLA-A,B,C in colorectal carcinoma is related to the degree of de-differentiation
- PMID: 3469275
- DOI: 10.1111/j.1744-313x.1986.tb01101.x
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Loss of HLA-A,B,C in colorectal carcinoma is related to the degree of de-differentiation
J Immunogenet.
1986 Apr-Jun.
Abstract
By means of immunoperoxidase staining of frozen sections 100 primary colorectal carcinomas and 19 metastases were studied for the expression of HLA-A,B,C antigens. A substantial number of the tumours showed a deficient class I expression. The loss of HLA-A,B,C correlated with the degree of de-differentiation.
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