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. 2021 Oct 6;3(13):1509-1511.
doi: 10.1016/j.jaccas.2021.07.023.

Stone Heart

Estefania De Garate  1   2   3 , Anna Baritussio  1 , Alessandra Scatteia  1 , Christopher Lawton  1 , Chiara Bucciarelli-Ducci  1   2   4
Affiliations

Stone Heart

Estefania De Garate et al. JACC Case Rep. .

Abstract

We describe a rare case of infiltrative cardiomyopathy characterized by multiple low-signal myocardial lesions consistent with nodular calcifications. A retrospectively detailed clinical history and the use of multimodality imaging enabled us to identify the final diagnosis. (Level of Difficulty: Advanced.).

Keywords: CMR, cardiac magnetic resonance; CT, computed tomography; LV, left ventricular; calcification; cardiac magnetic resonance; cardiomyopathy; computed tomography; imaging; myocardial infiltration.

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Conflict of interest statement

This work was supported by the NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health. Dr Bucciarelli-Ducci has reported being the CEO (part-time) of the Society for Cardiovascular Magnetic Resonance; and has received speaker fees from Circle Cardiovascular Imaging unrelated to the content of this work. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Imaging of Myocardial Calcifications (Left) Images of the left ventricle showing rounded lesions, which had low signal on all sequences (localizers: half-Fourier acquisition single-shot turbo spin echo imaging [HASTE], turbo spin echo T1, native T1 mapping, first-pass perfusion, and late gadolinium enhancement), thus confirming the calcific nature of the lesions (arrows). (Top left) Analysis of severely impaired longitudinal strain by a novel feature tracking technique. (Top right) Electrocardiogram of the patient showing left bundle branch block and first-degree atrioventricular block. (Middle right) Long-axis echocardiographic views showing severe mitral annulus calcification. (Bottom right) Chest computed tomography (CT) showing multiple hyperintense lesions involving the left ventricle and pericardium (arrows), thereby confirming the calcific nature of the lesions observed on cardiac magnetic resonance (CMR). 2D = 2-dimensional; STIR = short tau inversion recovery; SSFP = steady-state free precession.
See this image and copyright information in PMC

References

    1. Henderson R.R., Santiago L.M., Lombardo M., Spring D.A., Harrington A.R. Metastatic myocardial calcification in chronic renal failure presenting as atrioventricular block. N Engl J Med. 1971;284(22):1252–1253. - PubMed
    1. Nance J.W., Crane G.M., Halushka M.K., Fishman E.K., Zimmerman S.L. Myocardial calcifications: Pathophysiology, etiologies, differential diagnoses, and imaging findings. J Cardiovasc Comput Tomogr. 2015;9(1):58–67. - PubMed
    1. El Ghannudi S., Ohlmann P., Roy C. Idiopathic myocardial calcification: insights from multimodality imaging. Int J Cardiol. 2016;221:1053–1055. - PubMed

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