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. 2022 Apr;58(4):618-623.
doi: 10.1111/jpc.15786. Epub 2021 Oct 25.

Characteristics and outcomes of SARS-CoV-2 infection in Victorian children at a tertiary paediatric hospital

Shidan Tosif  1   2   3 , Laila F Ibrahim  1   2   3   4 , Rebecca Hughes  3 , Daryl R Cheng  1   2   3 , Danielle Wurzel  1   2   5   6 , Isabella Overmars  2 , Andrew C Steer  1   2   7 , Penelope A Bryant  1   2   4   7 , Trevor Duke  1   2   8 , Stuart Lewena  1   2   9   10 , Franz E Babl  1   9   10 , Sarah McNab  1   2   3 , Nigel Crawford  1   2   3
Affiliations

Characteristics and outcomes of SARS-CoV-2 infection in Victorian children at a tertiary paediatric hospital

Shidan Tosif et al. J Paediatr Child Health. 2022 Apr.

Abstract

Aim: Victoria experienced two 'waves' of COVID-19 between March and September 2020 and more cases than any other jurisdiction in Australia. Although world-wide reports of COVID-19 reflect that children are less likely to experience severe disease compared with adults, hospitalisations and deaths have been reported. We report testing and outcomes of children with SARS-CoV-2 infection presenting to a tertiary paediatric hospital in Melbourne.

Methods: We conducted a prospective cohort study at The Royal Children's Hospital (RCH), including all children and adolescents (aged 0-18 years) who presented and were tested for SARS-CoV-2 over a 6-month period, between 21 March 2020, up to the 21 September 2020. Detailed epidemiological and clinical data were recorded.

Results: A total of 19 708 tests for SARS-CoV-2 were performed in 14 419 patients. One hundred and eighty patients tested positive for SARS-CoV-2 (1.2%). 110 (61%) were symptomatic, 60 (33%) were asymptomatic and 10 (6%) were pre-symptomatic. Close contacts of a positive case were associated with a higher risk of a testing positive for SARS-CoV-2 (120/2027 (6%) vs. 60/14589 (0.4%), RD 5.5 (95% CI 4.5 to 6.5), P < 0.001). Eighteen (10%) SARS-CoV-2-positive patients were admitted to hospital with one patient requiring intensive care. All patients recovered fully with no deaths.

Conclusion: In Victorian children presenting to a tertiary hospital, SARS-CoV-2 infection caused predominantly mild or asymptomatic infection, with most children not requiring hospitalisation.

Keywords: COVID-19; general paediatrics; infectious disease.

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Figures

Fig 1
Fig 1
Number of SARS‐CoV‐2 tests and SARS‐CoV‐2‐positive cases by month. (formula image) SARS‐CoV‐2 tested and (formula image) SARS‐CoV‐2 positive.
See this image and copyright information in PMC

References

    1. World Health Organisation . WHO Coronavirus Disease (COVID‐19) Dashboard 2020. Available from: https://covid19.who.int/.
    1. Government of Canada . Coronavirus disease 2019 (COVID‐19): epidemiology update. Available from: https://health-infobase.canada.ca/covid-19/epidemiological-summary-covid....
    1. European Centre for Disease Prevention and Control . COVID‐19 in children and the role of school settings in COVID‐19 transmission. Stockholm, 2020.
    1. Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention . The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID‐19) in China. Zhonghua Liu Xing Bing Xue Za Zhi 2020; 41: 145–51. - PubMed
    1. Centre for Disease Control and Prevention . COVID Data Tracker 2020. Available from: https://covid.cdc.gov/covid-data-tracker/.