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. 2021 Dec;12(23):3255-3262.
doi: 10.1111/1759-7714.14197. Epub 2021 Oct 24.

Risk factors for surgical complications after anatomic lung resections in the era of VATS and ERAS

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Risk factors for surgical complications after anatomic lung resections in the era of VATS and ERAS

Christian Galata et al. Thorac Cancer. 2021 Dec.

Abstract

Background: The aim of this study was to identify risk factors for surgical complications after anatomic lung resections in the era of video-assisted thoracic surgery (VATS) and enhanced recovery after surgery (ERAS).

Methods: A retrospective analysis of all consecutive adult patients who underwent elective anatomic lung resections between January and December 2020 at our institution was performed.

Results: Eighty patients (40 VATS, 40 thoracotomy) were included. The 30-day mortality rate was 1.3%. The overall rate of major postoperative complications was 18.8%. Most major complications occurred in patients who underwent open surgery (complication rate 32.5%, share of total complications 86.7%). Major morbidity after VATS resection was rare (complication rate 2.5%, share of total complications 13.3%). In univariable analysis, thoracotomy (p = 0.003), impaired preoperative lung function (p = 0.003), complex surgery (p = 0.004) and sleeve resection (p = 0.037) were associated with adverse outcomes. In multivariable analysis, thoracotomy (p = 0.044) and impaired preoperative lung function (p = 0.028) were the only independent risk factors for major postoperative morbidity.

Conclusion: Thoracotomy was associated with a 10-fold increased risk for postoperative complications compared with minimally invasive surgery and was an independent risk factor for surgical complications. In the era of VATS and ERAS, the fact that thoracotomy is performed may be a reliable parameter to identify patients at risk for postoperative complications.

Keywords: VATS; enhanced recovery after surgery; postoperative complications; thoracic surgery; thoracotomy.

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Conflict of interest statement

The authors report no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Summary of the ERAS based clinical pathway. ERAS,enhanced recovery after surgery; NSAID, nonsteroidal anti‐inflammatory drug; PONV, postoperative nausea and vomiting; VATS, video‐assisted thoracoscopic surgery
FIGURE 2
FIGURE 2
Flowchart of the study population

References

    1. Yan TD, Black D, Bannon PG, McCaughan BC. Systematic review and meta‐analysis of randomized and nonrandomized trials on safety and efficacy of video‐assisted thoracic surgery lobectomy for early‐stage non‐small‐cell lung cancer. J Clin Oncol. 2009;27:2553–62. - PubMed
    1. Zhang Z, Zhang Y, Feng H, Yao Z, Teng J, Wei D, et al. Is video‐assisted thoracic surgery lobectomy better than thoracotomy for early‐stage non‐small‐cell lung cancer? A systematic review and meta‐analysis. Eur J Cardiothorac Surg. 2013;44:407–14. - PubMed
    1. Bendixen M, Jørgensen OD, Kronborg C, Andersen C, Licht PB. Postoperative pain and quality of life after lobectomy via video‐assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: a randomised controlled trial. Lancet Oncol. 2016;17:836–44. - PubMed
    1. Batchelor TJP, Rasburn NJ, Abdelnour‐Berchtold E, Brunelli A, Cerfolio RJ, Gonzalez M, et al. Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS). Eur J Cardiothorac Surg. 2019;55:91–115. - PubMed
    1. Martin LW, Sarosiek BM, Harrison MA, Hedrick T, Isbell JM, Krupnick AS, et al. Implementing a thoracic enhanced recovery program: lessons learned in the first year. Ann Thorac Surg. 2018;105:1597–604. - PubMed

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