Nanoparticles as elicitors and harvesters of economically important secondary metabolites in higher plants: A review

Abstract

Nanoparticles possess some unique properties which improve their biochemical reactivity. Plants, due to their stationary nature, are constantly exposed to nanoparticles present in the environment, which act as abiotic stress agents at sub-toxic concentrations and phytotoxic agents at higher concentrations. In general, nanoparticles exert their toxicological effect by the generation of reactive oxygen species to which plants respond by activating both enzymatic and non-enzymatic anti-oxidant defence mechanisms. One important manifestation of the defence response is the increased or de novo biosynthesis of secondary metabolites, many of which have commercial application. The present review extensively summarizes current knowledge about the application of different metallic, non-metallic and carbon-based nanoparticles as elicitors of economically important secondary metabolites in different plants, both in vivo and in vitro. Elicitation of secondary metabolites with nanoparticles in plant cultures, including hairy root cultures, is discussed. Another emergent technology is the ligand-harvesting of secondary metabolites using surface-functionalized nanoparticles, which is also mentioned. A brief explanation of the mechanism of action of nanoparticles on plant secondary metabolism is included. Optimum conditions and parameters to be evaluated and standardized for the successful commercial exploitation of this technology are also mentioned.

FIGURE 1

Schematic representation of the elicitation of secondary metabolites by currently known nanoparticles in plants

FIGURE 2

Schematic representation of biosynthesis of secondary metabolites by currently known nanoparticles in plant tissue cultures

FIGURE 3

Schematic diagram of ligand‐harvesting of secondary metabolites from intact plant cells by functionalized nanoparticles

FIGURE 4

Schematic representation of the probable mechanism of modulation of plant secondary mechanism by nanoparticles