Randomized Controlled Trial

. 2021 Dec 16;385(25):2395-2397.

doi: 10.1056/NEJMc2116018. Epub 2021 Oct 25.

Antibiotics versus Appendectomy for Acute Appendicitis - Longer-Term Outcomes

CODA Collaborative; Giana H Davidson¹, David R Flum¹, Sarah E Monsell¹, Lillian S Kao¹, Emily C Voldal¹, Patrick J Heagerty¹, Erin Fannon¹, Danielle C Lavallee¹, Bonnie Bizzell¹, Sarah O Lawrence¹, Bryan A Comstock¹, Anusha Krishnadasan¹, Robert J Winchell¹, Wesley H Self¹, Callie M Thompson¹, Farhood Farjah¹, Pauline K Park¹, Hasan B Alam¹, Darin Saltzman¹, Gregory J Moran¹, Amy H Kaji¹, Daniel A DeUgarte¹, Matthew Salzberg¹, Lisa Ferrigno¹, Katherine A Mandell¹, Thea P Price¹, Nicole Siparsky¹, Jacob Glaser¹, Patricia Ayoung-Chee¹, William Chiang¹, Jesse Victory¹, Bruce Chung¹, Damien W Carter¹, Matthew E Kutcher¹, Alan Jones¹, Julie Holihan¹, Mike K Liang¹, Brett A Faine¹, Joseph Cuschieri¹, Heather L Evans¹, Jeffrey Johnson¹, Joe H Patton¹, Natasha Coleman¹, Katherine Fischkoff¹, F Thurston Drake¹, Sabrina E Sanchez¹, Charles Parsons¹, Stephen R Odom¹, Larry G Kessler¹, David A Talan¹

Affiliations

Affiliation

¹ From University of Washington Medical Center-UW Medicine (G.H.D., D.R.F., E.F., D.C.L., B.B., S.O.L., F.F., L.G.K.), University of Washington (S.E.M., E.C.V., P.J.H., B.A.C.), Swedish Medical Center (K.A.M.), and Harborview Medical Center-UW Medicine (J.C., H.L.E.), Seattle, and Providence Regional Medical Center, Everett (J.G.) - all in Washington; McGovern Medical School, University of Texas Health Science Center (L.S.K.), Lyndon B. Johnson General Hospital, University of Texas (J.H., M.K.L.), and HCA Healthcare Kingwood, University of Houston (M.K.L.) - all in Houston; BC Academic Science Health Network, Vancouver, BC, Canada (D.C.L.); Olive View-UCLA Medical Center (A.K., D.S., G.J.M., D.A.T.), Harbor-UCLA Medical Center (A.H.K., D.A.D.), and UCLA Ronald Reagan Medical Center (D.A.T.), Los Angeles, and the University of California, San Francisco (J.C.) - all in California; Weill Cornell Medical Center (R.J.W.), Tisch Hospital, NYU Langone Medical Center (P.A.-C., W.C., J.V.), Bellevue Hospital Center, NYU School of Medicine (W.C.), and Columbia University Medical Center (N.C., K.F.) - all in New York; Vanderbilt University Medical Center, Nashville (W.H.S., C.M.T.); University of Utah, Salt Lake City (C.M.T.); University of Michigan Medical Center, Ann Arbor (P.K.P., H.B.A.), and Henry Ford Health System, Detroit (J.J., J.H.P.) - both in Michigan; UCHealth, University of Colorado Hospital, Denver (M.S., L.F.); Rush University Medical Center, Chicago (T.P.P., N.S.); Morehouse School of Medicine, Atlanta (P.A.-C.); Maine Medical Center, Portland (B.C., D.W.C.); University of Mississippi Medical Center, Jackson (M.E.K., A.J.); University of Iowa Hospitals and Clinics, Iowa City (B.A.F.); Medical University of South Carolina, Charleston (H.L.E.); and Boston University Medical Center (F.T.D., S.E.S.) and Beth Israel Deaconess Medical Center (C.P., S.R.O.) - both in Boston.

PMID: 34694761
DOI: 10.1056/NEJMc2116018

Randomized Controlled Trial

Antibiotics versus Appendectomy for Acute Appendicitis - Longer-Term Outcomes

CODA Collaborative et al. N Engl J Med. 2021.

. 2021 Dec 16;385(25):2395-2397.

doi: 10.1056/NEJMc2116018. Epub 2021 Oct 25.

Authors

Affiliation

¹ From University of Washington Medical Center-UW Medicine (G.H.D., D.R.F., E.F., D.C.L., B.B., S.O.L., F.F., L.G.K.), University of Washington (S.E.M., E.C.V., P.J.H., B.A.C.), Swedish Medical Center (K.A.M.), and Harborview Medical Center-UW Medicine (J.C., H.L.E.), Seattle, and Providence Regional Medical Center, Everett (J.G.) - all in Washington; McGovern Medical School, University of Texas Health Science Center (L.S.K.), Lyndon B. Johnson General Hospital, University of Texas (J.H., M.K.L.), and HCA Healthcare Kingwood, University of Houston (M.K.L.) - all in Houston; BC Academic Science Health Network, Vancouver, BC, Canada (D.C.L.); Olive View-UCLA Medical Center (A.K., D.S., G.J.M., D.A.T.), Harbor-UCLA Medical Center (A.H.K., D.A.D.), and UCLA Ronald Reagan Medical Center (D.A.T.), Los Angeles, and the University of California, San Francisco (J.C.) - all in California; Weill Cornell Medical Center (R.J.W.), Tisch Hospital, NYU Langone Medical Center (P.A.-C., W.C., J.V.), Bellevue Hospital Center, NYU School of Medicine (W.C.), and Columbia University Medical Center (N.C., K.F.) - all in New York; Vanderbilt University Medical Center, Nashville (W.H.S., C.M.T.); University of Utah, Salt Lake City (C.M.T.); University of Michigan Medical Center, Ann Arbor (P.K.P., H.B.A.), and Henry Ford Health System, Detroit (J.J., J.H.P.) - both in Michigan; UCHealth, University of Colorado Hospital, Denver (M.S., L.F.); Rush University Medical Center, Chicago (T.P.P., N.S.); Morehouse School of Medicine, Atlanta (P.A.-C.); Maine Medical Center, Portland (B.C., D.W.C.); University of Mississippi Medical Center, Jackson (M.E.K., A.J.); University of Iowa Hospitals and Clinics, Iowa City (B.A.F.); Medical University of South Carolina, Charleston (H.L.E.); and Boston University Medical Center (F.T.D., S.E.S.) and Beth Israel Deaconess Medical Center (C.P., S.R.O.) - both in Boston.

PMID: 34694761
DOI: 10.1056/NEJMc2116018

No abstract available

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Comment in

Management of Acute Appendicitis - Longer-Term Outcomes.
Newdow M. Newdow M. N Engl J Med. 2022 Mar 3;386(9):900. doi: 10.1056/NEJMc2200552. N Engl J Med. 2022. PMID: 35235739 No abstract available.

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Antibiotics versus Appendectomy for Acute Appendicitis - Longer-Term Outcomes

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