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Case Reports
. 2021 Sep 29;9(10):1103.
doi: 10.3390/vaccines9101103.

Pulmonary Infection Caused by Mycobacterium malmoense in a Chronic HIV-Infected Individual Participating in a Therapeutic Vaccine Trial

Joana Silva Marques  1   2 , Marta Bodro  1 , Berta Torres  1 , Felipe García  1 , José Antonio Martínez  1 , Lorna Leal  1
Affiliations
Case Reports

Pulmonary Infection Caused by Mycobacterium malmoense in a Chronic HIV-Infected Individual Participating in a Therapeutic Vaccine Trial

Joana Silva Marques et al. Vaccines (Basel). .

Abstract

We report a case of Mycobacterium malmoense pulmonary infection and HIV-1 chronic co-infection in a 60-year-old man while participating in an HIV-1 therapeutic vaccine clinical trial and during the analytical treatment interruption. We present clinical and therapeutic features of a complicated M. malmoense pulmonary infection along with discussion of the possible relation to the HIV-1 cure-related interventions.

Keywords: HIV; Mycobacterium malmoense; therapeutic vaccine.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Lung images: (1) lung chest X-ray at diagnosis shows a left apical cavitation and surrounding infiltrate; (2) lung chest CT scan after clinical impairment shows central emphysema, fibrosis in both upper lobes with significant loss of volume, apical left lobe and diffuse bronchiectasis and a large apical cavity in left lung of approximately 7.1 cm.
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