Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Feb;84(4):1015-9.
doi: 10.1073/pnas.84.4.1015.

On the translocation of proteins across membranes

S J Singer, P A Maher, M P Yaffe

On the translocation of proteins across membranes

S J Singer et al. Proc Natl Acad Sci U S A. 1987 Feb.

Abstract

Many proteins of intracellular organelles are first synthesized in the cytoplasm and are then specifically transferred across the membranes of the organelles. On the assumption that these transfers all occur by the same basic mechanism, we enumerate the rather stringent requirements that the mechanism must satisfy. A unitary molecular mechanism is then proposed that meets these requirements.

PubMed Disclaimer

References

    1. EMBO J. 1986 Jan;5(1):161-5 - PubMed
    1. Cell. 1983 May;33(1):231-40 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4028-30 - PubMed
    1. Cell. 1985 Nov;43(1):351-60 - PubMed
    1. Eur J Biochem. 1979 Jun;97(1):175-81 - PubMed

LinkOut - more resources