Metronidazole-induced neurotoxicity

doi:10.1503/cmaj.201671

. 2021 Oct 25;193(42):E1630.

doi: 10.1503/cmaj.201671.

Metronidazole-induced neurotoxicity

Danica Quickfall¹, Nick Daneman¹, Adam A Dmytriw¹, David N Juurlink²

Affiliations

¹ Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
² Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont. david.juurlink@ices.on.ca.

PMID: 34697097
PMCID: PMC8562982
DOI: 10.1503/cmaj.201671

Metronidazole-induced neurotoxicity

Danica Quickfall et al. CMAJ. 2021.

. 2021 Oct 25;193(42):E1630.

doi: 10.1503/cmaj.201671.

Authors

Danica Quickfall¹, Nick Daneman¹, Adam A Dmytriw¹, David N Juurlink²

Affiliations

¹ Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
² Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont. david.juurlink@ices.on.ca.

PMID: 34697097
PMCID: PMC8562982
DOI: 10.1503/cmaj.201671

No abstract available

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Conflict of interest statement

Competing interests: None declared.

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References

1. Daneman N, Cheng Y, Gomes T, et al. . Metronidazole-associated neurologic events: a nested case-control study. Clin Infect Dis 2021;72:2095–100. - PMC - PubMed
1. Sørensen CG, Karlsson WK, Amin FM, et al. . Metronidazole-induced encephalopathy: a systematic review. J Neurol 2020; 267:1–13. - PubMed
1. Kuriyama A, Jackson JL, Doi A, et al. . Metronidazole-induced central nervous system toxicity: a systematic review. Clin Neuropharmacol 2011;34:241–7. - PubMed
1. Patel L, Batchala P, Almardawi R, et al. . Acute metronidazole-induced neurotoxicity: an update on MRI findings. Clin Radiol 2020;75:202–8. - PubMed

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[1] Daneman N, Cheng Y, Gomes T, et al. . Metronidazole-associated neurologic events: a nested case-control study. Clin Infect Dis 2021;72:2095–100. - PMC - PubMed

[2] Daneman N, Cheng Y, Gomes T, et al. . Metronidazole-associated neurologic events: a nested case-control study. Clin Infect Dis 2021;72:2095–100. - PMC - PubMed

[3] Sørensen CG, Karlsson WK, Amin FM, et al. . Metronidazole-induced encephalopathy: a systematic review. J Neurol 2020; 267:1–13. - PubMed

[4] Sørensen CG, Karlsson WK, Amin FM, et al. . Metronidazole-induced encephalopathy: a systematic review. J Neurol 2020; 267:1–13. - PubMed

[5] Kuriyama A, Jackson JL, Doi A, et al. . Metronidazole-induced central nervous system toxicity: a systematic review. Clin Neuropharmacol 2011;34:241–7. - PubMed

[6] Kuriyama A, Jackson JL, Doi A, et al. . Metronidazole-induced central nervous system toxicity: a systematic review. Clin Neuropharmacol 2011;34:241–7. - PubMed

[7] Patel L, Batchala P, Almardawi R, et al. . Acute metronidazole-induced neurotoxicity: an update on MRI findings. Clin Radiol 2020;75:202–8. - PubMed

[8] Patel L, Batchala P, Almardawi R, et al. . Acute metronidazole-induced neurotoxicity: an update on MRI findings. Clin Radiol 2020;75:202–8. - PubMed

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Metronidazole-induced neurotoxicity

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Metronidazole-induced neurotoxicity

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