Sun Exposure and Vitamin D
- PMID: 34698034
- DOI: 10.1159/000517640
Sun Exposure and Vitamin D
Abstract
Vitamin D is generally accepted in its importance on the regulation of calcium homeostasis and bone metabolism. Moreover, further health effects due to vitamin D are under discussion. In its effect, vitamin D is more like a hormone. In the classic view, a vitamin is an essential nutrient, which cannot be synthesized independently in the body. Besides nutrition, vitamin D will be produced in the body itself. The skin contains the provitamin D3 7-dehydrocholesterol, a precursor of vitamin D. Provitamin D3 will be photoconverted to previtamin D3 by UVB radiation that penetrates the skin superficially. In this way, the vitamin D metabolism will be started independent of the nutrition. In everyday life, this photosynthesis will be carried out due to the solar UVB radiation penetrating the uncovered skin. In the same spectral waveband range of UVB radiation, which causes the beneficial health effect of starting the vitamin D metabolism, the UVB radiation causes simultaneously acute and chronic harmful health effects as UV erythema (sunburn), skin aging and skin cancer. There is no vitamin D production in the skin without simultaneous DNA damage in the skin. Against this background, risks and benefits have to be balanced carefully.
© 2021 S. Karger AG, Basel.
Similar articles
-
Photosynthesis of vitamin D in the skin: effect of environmental and life-style variables.Fed Proc. 1987 Apr;46(5):1876-82. Fed Proc. 1987. PMID: 3030826
-
Optimal sunscreen use, during a sun holiday with a very high ultraviolet index, allows vitamin D synthesis without sunburn.Br J Dermatol. 2019 Nov;181(5):1052-1062. doi: 10.1111/bjd.17888. Epub 2019 May 24. Br J Dermatol. 2019. PMID: 31069787 Free PMC article. Clinical Trial.
-
Sunlight, ultraviolet radiation, vitamin D and skin cancer: how much sunlight do we need?Adv Exp Med Biol. 2014;810:1-16. Adv Exp Med Biol. 2014. PMID: 25207357 Review.
-
Safe, mild ultraviolet-B exposure: An essential human requirement for vitamin D and other vital bodily parameter adequacy: A review.Photodermatol Photoimmunol Photomed. 2020 Nov;36(6):417-423. doi: 10.1111/phpp.12584. Epub 2020 Aug 9. Photodermatol Photoimmunol Photomed. 2020. PMID: 32623756 Free PMC article. Review.
-
Is the action spectrum for the UV-induced production of previtamin D3 in human skin correct?Photochem Photobiol Sci. 2010 Jan;9(1):11-7. doi: 10.1039/b9pp00012g. Epub 2009 Oct 19. Photochem Photobiol Sci. 2010. PMID: 20062839 Review.
Cited by
-
Vitamin D levels and its influencing factors in children and adolescents in mainland China: a systematic review and meta-analysis.BMJ Open. 2025 Jun 26;15(6):e094693. doi: 10.1136/bmjopen-2024-094693. BMJ Open. 2025. PMID: 40578884 Free PMC article.
-
The Impact of Sunlight Exposure on Postoperative Hypoparathyroidism: A Retrospective Analysis from Two Greek Centers.J Clin Med. 2025 Jun 21;14(13):4418. doi: 10.3390/jcm14134418. J Clin Med. 2025. PMID: 40648792 Free PMC article.
-
Exploiting Vitamin D Receptor and Its Ligands to Target Squamous Cell Carcinomas of the Head and Neck.Int J Mol Sci. 2023 Feb 28;24(5):4675. doi: 10.3390/ijms24054675. Int J Mol Sci. 2023. PMID: 36902107 Free PMC article.
-
The Course of Minipuberty in Daughters of Women with Low Gestational Vitamin D Status.Nutrients. 2024 Jul 21;16(14):2362. doi: 10.3390/nu16142362. Nutrients. 2024. PMID: 39064805 Free PMC article.
-
The Association between Vitamin D Levels and Thrombus Burden in Patients with ST-Elevation Myocardial Infarction.J Tehran Heart Cent. 2022 Apr;17(2):48-55. doi: 10.18502/jthc.v17i2.9835. J Tehran Heart Cent. 2022. PMID: 36567933 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical