Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Oct-Dec;43(4):344-354.
doi: 10.1097/TME.0000000000000376.

Whole Blood for Resuscitation of Traumatic Hemorrhagic Shock in Adults

Affiliations
Review

Whole Blood for Resuscitation of Traumatic Hemorrhagic Shock in Adults

Allison R Jones et al. Adv Emerg Nurs J. 2021 Oct-Dec.

Abstract

Injured patients with traumatic hemorrhagic shock often require resuscitation with transfusion of red blood cells, plasma, and platelets. Resuscitation with whole blood (WB) has been used in military settings, and its use is increasingly common in civilian practice. We provide an overview of the benefits and challenges, guidelines, and unanswered questions related to the use of WB in the treatment of civilian trauma-related hemorrhage. Implications for advanced practice nurses and nursing staff are also discussed.

PubMed Disclaimer

Conflict of interest statement

Disclosure: The authors report no conflicts of interest.

References

    1. American Association of Blood Banks, The American Red Cross, America’s Blood Centers, & Armed Services Blood Program. (2017). Circular of information for the use of human blood and blood components https://www.aabb.org/tm/coi/Documents/coi1017.pdf
    1. Auten JD, Lunceford NL, Horton JL, Galarneau MR, Galindo RM, Shepps CD, Zieber TJ, & Dewing CB (2015). The safety of early fresh, whole blood transfusion among severely battle injured at US Marine Corps forward surgical care facilities in Afghanistan. Journal of Trauma & Acute Care Surgery, 79(5), 790–796. 10.1097/TA.0000000000000842 - DOI - PubMed
    1. Bahr TM, DuPont TL, Morris DS, Pierson SE, Esplin MS, Brown SM, O’Brien EA, Ilstrup SJ, & Christensen RD (2019). First report of using low-titer cold-stored type O whole blood in massive postpartum hemorrhage. Transfusion, 59(10), 3089–3092. 10.1111/trf.15492 - DOI - PubMed
    1. Bianchi M, Vaglio S, Pupella S, Marano G, Facco G, Liumbruno GM, & Grazzini G (2016). Leucoreduction of blood components: An effective way to increase blood safety? Blood Transfusion, 14(2), 214–227. 10.2450/2015.0154-15 - DOI - PMC - PubMed
    1. Bilgin YM, van de Watering LM, & Brand A (2011). Clinical effects of leucoreduction of blood transfusions. The Netherlands Journal of Medicine, 69(10), 441–450. - PubMed