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Comment
. 2021 Nov;297(5):101242.
doi: 10.1016/j.jbc.2021.101242. Epub 2021 Oct 23.

SARS-CoV-2 Y453F is not the "cluster 5" variant

Ria Lassaunière  1
Affiliations
Comment

SARS-CoV-2 Y453F is not the "cluster 5" variant

Ria Lassaunière. J Biol Chem. 2021 Nov.
No abstract available

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Conflict of interest statement

Conflict of interest The author declares no conflicts of interests with the contents of this article.

Figures

Figure 1
Figure 1
The crystal structure of a closed prefusion SARS-CoV-2 spike trimer [PDB:6ZGE] indicating the amino acid changes oftwo different variants.A, the SARS-CoV-2 cluster 5 variant described in a preliminary report by Statens Serum Institut (3, 4); and B, the SARS-CoV-2 Y453F receptor-binding domain (RBD) variant studied by Bayarri-Olmos et al. (1). Red spheres indicate the positions of amino acid changes. The RBD is presented in green, the N-terminal domain (NTD) in beige, and the S2 domain in gray. The regions encompassing the S1147L and M1229I substitutions are not within the crystal structure; however, their relative positions are indicated.
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References

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