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Review
. 2021 Oct;29(10):1205-1215.
doi: 10.1016/j.jsps.2021.09.004. Epub 2021 Sep 20.

Autoinjector - A smart device for emergency cum personal therapy

Affiliations
Review

Autoinjector - A smart device for emergency cum personal therapy

Anitha Roy et al. Saudi Pharm J. 2021 Oct.

Abstract

Autoinjectors are self-injectable devices; they are important class of medical devices which can deliver drugs through subcutaneous or intramuscular route. They enclose prefilled syringes or cartridges which are driven by a spring system. The major benefits of this device are easy self-administration, improved patient compliance, reduced anxiety, and dosage accuracy. Immediate treatment during emergency conditions such as anaphylaxis, migraine, and status epilepticus or for chronic conditions like psoriasis, diabetes, multiple sclerosis, and rheumatoid arthritis, Reformulation of first-generation biologics, technical advancements, innovative designs, patient compliance, overwhelming interest for self-administration all these made entry of more and more autoinjectors into use. In this review, intensive efforts have been made for exploring the different types of currently available autoinjectors for the management of emergency and chronic diseases.

Keywords: Autoinjector; Chronic diseases; Emergency condition; Medical device.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Commercially available autoinjectors for drug delivery. (Adopted from https://www.ondrugdelivery.com, Accessed on 01 March 2021.)

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Further Reading

    1. Schwarzenbach F., Dao Trong M., Grange L., Laurent P.E., Abry H., Cotten J., Granger C. Results of a human factors experiment of the usability and patient acceptance of a new autoinjector in patients with rheumatoid arthritis. Patient Prefer Adherence. 2014:199. - PMC - PubMed
    1. Sheikh S.Z., Hammer A.E., Fox N.L., Groark J., Struemper H., Roth D., Gordon D. Evaluation of a novel autoinjector for subcutaneous self-administration of belimumab in systemic lupus erythematosus. Int. J. Clin. Pharmacol. Ther. 2016;54:914–922. - PMC - PubMed
    1. Stohl, W., Metyas, S., Tan, S.M., Cheema, G.S., Oamar, B., Xu, D., Roschke, V., Y, W., Hilbert, B.K.P., D M, 2003. B-lymphocyte stimulator over expression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis 3475–86. - PubMed

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