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. 2021 Nov 1;26(6):e691-e702.
doi: 10.4317/medoral.24256.

Clinical management of alveolar osteitis. A systematic review

F Garola  1 , G Gilligan, R Panico, N Leonardi, E Piemonte
Affiliations

Clinical management of alveolar osteitis. A systematic review

F Garola et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Background: Alveolar Osteitis (AO) is one of the most common complications of tooth extraction. Several therapeutic interventions have been described for the treatment of AO, however, there are no treatment standardized protocols. The aim of this study was to conduct a systematic review on the efficacy in pain control of the different treatments for AO. The feasibility of the application of these interventions is also discussed.

Material and methods: A structured electronic and hand search strategy was applied to PubMed, Scopus, Cochrane Library, OpenGrey, and Google Scholar between January 2010 and July 2020 to identify studies according to PRISMA guidelines. The inclusion criteria were original English and Spanish clinical trials that analyzed pain-control parameters according to visual analog scale (VAS, 0-10 scale), or pain relief patients' percentages. Those treatments that reach VAS ≤ 4 on day 2 or before; or ≥ 85% of patients with absence of pain symptoms at day 7 or before were considered acceptable for their recommendation.

Results: The final review included 17 clinical trials. Among them, there were analyzed a total of 39 different AO treatments. 53,8% of the treatments fulfill the proposed parameters for pain control.

Conclusions: Treatment alternatives are multiple, heterogeneous, and difficult to compare. The management of AO is summarized in basic (intra-alveolar irrigation) and specific procedures (Alveogyl®, Neocones®, SaliCept Patch®, Low-Level Laser, Platelet-Rich Fibrin) that reach pain control success. They could be selected according to their availability and advantages or disadvantages.

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Conflict of interest statement

Conflicts of interest The authors declare that there is no conflict of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1
Figure 1
PRISMA flowchart of systematic review search process.
Figure 2
Figure 2
Risk of bias summary for randomized controlled trials, assessed using the Cochrane Risk of Bias (RoB) tool: review authors' judgments about each risk of bias item for each included study (+ = low; − = high;? = unclear).
Figure 3
Figure 3
Risk of bias summary for non-randomized controlled trials, assessed using The Risk Of Bias In Non-randomized Studies of Interventions ROBINS-I tool.
See this image and copyright information in PMC

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