Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2022 Jan;33(1):15-24.
doi: 10.1007/s10552-021-01509-y. Epub 2021 Oct 27.

Application of theoretical frameworks on human papillomavirus vaccine interventions in the United States: systematic review and meta-analysis

Cesia Cotache-Condor  1 , Matthew Peterson  2 , Matthew Asare  3
Affiliations
Meta-Analysis

Application of theoretical frameworks on human papillomavirus vaccine interventions in the United States: systematic review and meta-analysis

Cesia Cotache-Condor et al. Cancer Causes Control. 2022 Jan.

Abstract

Purpose: Theoretical frameworks are useful tools to explain the dynamics of behavioral change, develop, and implement intervention studies. The purpose of this systematic review and meta-analysis is to evaluate the application of theoretical frameworks and models to HPV vaccination intervention studies in the United States (US) from January 2006 to December 2019.

Methods: A comprehensive search across databases, including PubMed, EMBASE, ERIC, CINAHL, Academic Search Complete, Scopus, Web of Science, and PsycINFO, was conducted. Articles were included in the systematic analysis if at least one theory was used to develop the intervention phase. All intervention studies targeting populations in the US without restrictions of age, income, sex, and ethnicity were included. Articles were included in the meta-analysis if vaccine uptake and/or vaccine completion was addressed.

Results: The Health Belief Model, Motivational Interviewing, Theory of Planned Behavior, and Information-Motivation-Behavioral Skills were the most used theories. Based on theory integrity, theory rationale, and theory operationalization, most of the studies (60%) were rated high for the application of the theoretical frameworks. Our results suggest a preference for theoretical frameworks targeting individual change rather than community change and the existence of gender disparities in the application of theoretical frameworks. The association between theory and increase of likelihood in vaccine uptake and completion was not supported.

Conclusion: This review spotlights common issues in the application of theoretical frameworks in HPV vaccine interventions in the US. Our results suggest we are still in a developmental phase on several aspects of theory application to HPV vaccination.

Keywords: HPV intervention; HPV vaccination; Meta-analysis; Systematic review; Theoretical framework.

PubMed Disclaimer

References

    1. Centers for Disease Control and Prevention (2019) About HPV. Available at https://www.cdc.gov/hpv/index.html . Accessed 10 May, 2019
    1. World Health Organization (2017) Human papillomavirus vaccines: WHO position paper, May 2017-recommendations. Vaccine 35(43):5753–5755. https://doi.org/10.1016/j.vaccine.2017.05.069 - DOI
    1. Centers for Disease Control and Prevention (2019) Human papillomavirus vaccination for adults: updated recommendations of the Advisory Committee on immunization practices. Available at https://www.cdc.gov/mmwr/volumes/68/wr/mm6832a3.htm . Accessed 27 Mar, 2021
    1. Peterson CE, Dykens JA, Brewer NT, Buscemi J, Watson K, Comer-Hagans D, Ramamonjiarivelo Z, Fitzgibbon M (2016) Society of behavioral medicine supports increasing HPV vaccination uptake: an urgent opportunity for cancer prevention. Transl Behav Med 6(4):672–675. https://doi.org/10.1007/s13142-016-0441-5 - DOI - PubMed - PMC
    1. Healthy people 2020 (2019) Immunization and infectious diseases. Available at https://www.healthypeople.gov/2020/topics-objectives/topic/immunization-... . Accessed 23 Aug, 2019

Substances

LinkOut - more resources