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. 2021 Oct;171(6):745-749.
doi: 10.1007/s10517-021-05308-y. Epub 2021 Oct 27.

Effect of Disinfectants with Different Active Ingredients on Biofilm Formation in Pseudomonas aeruginosa

E V Grigorova  1 , U M Nemchenko  2 , N M Voropaeva  2 , N L Belkova  2 , O A Noskova  2 , E D Savilov  2
Affiliations

Effect of Disinfectants with Different Active Ingredients on Biofilm Formation in Pseudomonas aeruginosa

E V Grigorova et al. Bull Exp Biol Med. 2021 Oct.

Abstract

We compared the effects of disinfectants on biofilms of 10 Pseudomonas aeruginosa strains isolated from different loci of patients with purulent-septic infections. Identification was carried out by standard bacteriological methods. To substantiate the prospects of using in hospitals and to assess the effect of disinfectants on P. aeruginosa biofilms, the following disinfectants were used in various concentrations: Sekusept Aktiv, A-DEZ, and Monitor Oxy. All clinical strains of P. aeruginosa showed the ability to form biofilms. Both oxygen-containing and quaternary ammonium compounds effectively inhibited the formation of biofilms. In more than 50% cases, disinfectants with different active ingredients did not destroy pre-formed of P. aeruginosa biofilms.

Keywords: Pseudomonas aeruginosa; biofilm formation; disinfectants; purulent-septic infections.

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