Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep 15;3(9):000194.
doi: 10.1099/acmi.0.000194. eCollection 2021.

Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system

Affiliations

Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system

Richard M Mariita et al. Access Microbiol. .

Abstract

Hospital-associated infections (HAIs) are a major burden in healthcare systems. In this study, UVC LEDs emitting radiation from 260 to 270 nm were evaluated for effectiveness in reducing methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii . The array has four WD LEDs, each with 70 mW placed at 7 cm from test organisms. With 11.76 mJ cm-2, the study obtained 99.99% reduction (log10 reduction factor of 4) against MRSA and VRE. For A. baumannii , 9 mJ cm-2 obtained 99.999% reduction (log10 reduction factor of 5). These results present scientific evidence on how effective UVC LEDs can be used in the fight against HAIs.

Keywords: Acinetobacter baumannii; HVAC; UVC LEDs; disinfection; healthcare-associated infections; methicillin-resistant Staphylococcus aureus (MRSA); vancomycin-resistant enterococcus faecium.

PubMed Disclaimer

Conflict of interest statement

Both R. M. M. and R. V. R. work for Crystal IS, an Asahi Kasei company that manufactures UVC LEDs.

Figures

Fig. 1.
Fig. 1.
Disinfection efficacy of UVC against key pathogens associated with HAIs. A. baumannii was more sensitive against UVC compared to MRSA and VRE.

References

    1. De Angelis G, Murthy A, Beyersmann J, Harbarth S. Estimating the impact of healthcare-associated infections on length of stay and costs. Clin Microbiol Infect. 2010;16:1729–1735. doi: 10.1111/j.1469-0691.2010.03332.x. - DOI - PubMed
    1. Stone PW. Economic burden of healthcare-associated infections: An american perspective. Expert Rev Pharmacoecon Outcomes Res. 2009;9:417–422. doi: 10.1586/erp.09.53. - DOI - PMC - PubMed
    1. David MZ, Daum RS. Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev. 2010;23:616–687. doi: 10.1128/CMR.00081-09. - DOI - PMC - PubMed
    1. Kavanagh KT. Control of MSSA and MRSA in the United States: protocols, policies, risk adjustment and excuses. Antimicrob Resist Infect Control. 2019;8:1–8. - PMC - PubMed
    1. Valiquette L, Chakra CNA, Laupland KB. Financial impact of health care-associated infections: When money talks. Can J Infect Dis Med Microbiol. 2014;25:71–74. doi: 10.1155/2014/279794. - DOI - PMC - PubMed

LinkOut - more resources