Success Factors of Artificial Intelligence Implementation in Healthcare
- PMID: 34713083
- PMCID: PMC8521923
- DOI: 10.3389/fdgth.2021.594971
Success Factors of Artificial Intelligence Implementation in Healthcare
Abstract
Background: Artificial Intelligence (AI) in healthcare has demonstrated high efficiency in academic research, while only few, and predominantly small, real-world AI applications exist in the preventive, diagnostic and therapeutic contexts. Our identification and analysis of success factors for the implementation of AI aims to close the gap between recent years' significant academic AI advancements and the comparably low level of practical application in healthcare. Methods: A literature and real life cases analysis was conducted in Scopus and OpacPlus as well as the Google advanced search database. The according search queries have been defined based on success factor categories for AI implementation derived from a prior World Health Organization survey about barriers of adoption of Big Data within 125 countries. The eligible publications and real life cases were identified through a catalog of in- and exclusion criteria focused on concrete AI application cases. These were then analyzed to deduct and discuss success factors that facilitate or inhibit a broad-scale implementation of AI in healthcare. Results: The analysis revealed three categories of success factors, namely (1) policy setting, (2) technological implementation, and (3) medical and economic impact measurement. For each of them a set of recommendations has been deducted: First, a risk adjusted policy frame is required that distinguishes between precautionary and permissionless principles, and differentiates among accountability, liability, and culpability. Second, a "privacy by design" centered technology infrastructure shall be applied that enables practical and legally compliant data access. Third, the medical and economic impact need to be quantified, e.g., through the measurement of quality-adjusted life years while applying the CHEERS and PRISMA reporting criteria. Conclusions: Private and public institutions can already today leverage AI implementation based on the identified results and thus drive the translation from scientific development to real world application. Additional success factors could include trust-building measures, data categorization guidelines, and risk level assessments and as the success factors are interlinked, future research should elaborate on their optimal interaction to utilize the full potential of AI in real world application.
Keywords: artificial intelligence; digital health; impact measurement; policy framework; public health; success factor; technology assessment.
Copyright © 2021 Wolff, Pauling, Keck and Baumbach.
Conflict of interest statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Figures







Similar articles
-
ARTIFICIAL INTELLIGENCE IN MEDICAL PRACTICE: REGULATIVE ISSUES AND PERSPECTIVES.Wiad Lek. 2020;73(12 cz 2):2722-2727. Wiad Lek. 2020. PMID: 33611272 Review.
-
Bridging the Gap: From AI Success in Clinical Trials to Real-World Healthcare Implementation-A Narrative Review.Healthcare (Basel). 2025 Mar 22;13(7):701. doi: 10.3390/healthcare13070701. Healthcare (Basel). 2025. PMID: 40217999 Free PMC article. Review.
-
Exploring Physician Perspectives on Using Real-world Care Data for the Development of Artificial Intelligence-Based Technologies in Health Care: Qualitative Study.JMIR Form Res. 2022 May 18;6(5):e35367. doi: 10.2196/35367. JMIR Form Res. 2022. PMID: 35583921 Free PMC article.
-
Challenges and solutions for transforming health ecosystems in low- and middle-income countries through artificial intelligence.Front Med (Lausanne). 2022 Dec 2;9:958097. doi: 10.3389/fmed.2022.958097. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36530888 Free PMC article.
-
The future of Cochrane Neonatal.Early Hum Dev. 2020 Nov;150:105191. doi: 10.1016/j.earlhumdev.2020.105191. Epub 2020 Sep 12. Early Hum Dev. 2020. PMID: 33036834
Cited by
-
Adapting Clinical Guidelines for the Digital Age: Summary of a Holistic and Multidisciplinary Approach.Am J Med Qual. 2023 Sep-Oct 01;38(5S Suppl 2):S3-S11. doi: 10.1097/JMQ.0000000000000138. Epub 2023 Sep 5. Am J Med Qual. 2023. PMID: 37668270 Free PMC article.
-
Artificial intelligence tool development: what clinicians need to know?BMC Med. 2025 Apr 24;23(1):244. doi: 10.1186/s12916-025-04076-0. BMC Med. 2025. PMID: 40275334 Free PMC article. Review.
-
Is Artificial Intelligence the Cost-Saving Lens to Diabetic Retinopathy Screening in Low- and Middle-Income Countries?Cureus. 2023 Sep 19;15(9):e45539. doi: 10.7759/cureus.45539. eCollection 2023 Sep. Cureus. 2023. PMID: 37868419 Free PMC article. Review.
-
Machine Learning in Clinical Trials: A Primer with Applications to Neurology.Neurotherapeutics. 2023 Jul;20(4):1066-1080. doi: 10.1007/s13311-023-01384-2. Epub 2023 May 30. Neurotherapeutics. 2023. PMID: 37249836 Free PMC article. Review.
-
Implementing AI in Hospitals to Achieve a Learning Health System: Systematic Review of Current Enablers and Barriers.J Med Internet Res. 2024 Aug 2;26:e49655. doi: 10.2196/49655. J Med Internet Res. 2024. PMID: 39094106 Free PMC article.
References
-
- German Bundestag . Available online at: https://dip21.bundestag.de/dip21/btd/19/134/1913438.pdf
-
- Bundesanzeiger Verlag www.bundesanzeiger-verlag.de. Das Bundesgesetzblatt (BGBl.) - Bundesanzeiger Verlag. Bundesanzeiger Verlagsgesellschaft mbH. (2020). Available online at: https://www.bgbl.de/xaver/bgbl/text.xav?SID=&tf=xaver.component.Text_0&t...
LinkOut - more resources
Full Text Sources
Miscellaneous