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Case Reports
. 2021 Nov;38(6):1575-1576.
doi: 10.1111/pde.14849. Epub 2021 Oct 29.

Neonatal pemphigoid gestationis: An atypical presentation of a rare disease

Amber Jimenez  1 , Kimberly Blain  2 , Mazdak Khalighi  2 , Jennie T Clarke  2 , Jeremy Snook  2 , Sarah D Cipriano  2
Affiliations
Case Reports

Neonatal pemphigoid gestationis: An atypical presentation of a rare disease

Amber Jimenez et al. Pediatr Dermatol. 2021 Nov.

Abstract

Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by urticarial plaques and/or vesicles and tense bullae. A unique presentation of BP can occur during pregnancy, the postpartum period after delivery, or with the initiation of contraception, in which case it is referred to as pemphigoid gestationis (PG). In rare instances, newborns born to mothers with PG may also present with blisters due to transplacental passage of maternal anti-bullous pemphigoid 180 (BP180) or 230 (BP230) immunoglobulin G (IgG). In this report, we present an unusual case of neonatal PG in an infant born to an asymptomatic mother without a previous diagnosis of PG.

Keywords: bullous disease-immunologic; dermatopathology; immunobullous disease; neonatal.

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References

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