Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Nov;32(11):2687-2689.
doi: 10.1681/ASN.2021081038.

Beyond Transcription Factors: Remodeling Chromatin in the Metanephric Mesenchyme

Affiliations
Editorial

Beyond Transcription Factors: Remodeling Chromatin in the Metanephric Mesenchyme

Samir S El-Dahr. J Am Soc Nephrol. 2021 Nov.
No abstract available

Keywords: chromatin remodeling; kidney development; metanephric mesenchyme; mouse; transcription factors.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
A schematic summary of the manuscript by Li et al. depicting the functions of the Six2-Eya1/Brg1 complex in mouse MM and nephron progenitor cells. E, Embryonic.

Comment on

References

    1. Centore RC, Sandoval GJ, Soares LMM, Kadoch C, Chan HM: Mammalian SWI/SNF chromatin remodeling complexes: Emerging mechanisms and therapeutic strategies. Trends Genet 36: 936–950, 2020 - PubMed
    1. Hilliard S, Song R, Liu H, Chen CH, Li Y, Baddoo M, et al. : Defining the dynamic chromatin landscape of mouse nephron progenitors. Biol Open 8: bio042754, 2019 - PMC - PubMed
    1. Ranghini EJ, Dressler GR: Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms. Dev Biol 399: 296–305, 2015 - PMC - PubMed
    1. Zhang L, Ettou S, Khalid M, Taglienti M, Jain D, Jung YL, et al. : EED, a member of the polycomb group, is required for nephron differentiation and the maintenance of nephron progenitor cells. Development 145: dev157149, 2018 - PMC - PubMed
    1. Liu H, Hilliard S, Kelly E, Chen CH, Saifudeen Z, El-Dahr SS: The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice. J Biol Chem 295: 11542–11558, 2020 - PMC - PubMed

LinkOut - more resources