Outer membrane vesicle vaccines for Neisseria gonorrhoeae
- PMID: 34716431
- PMCID: PMC8555735
- DOI: 10.1038/s41585-021-00534-5
Outer membrane vesicle vaccines for Neisseria gonorrhoeae
Abstract
Multidrug-resistant Neisseria gonorrhoeae is a global health problem, and the development of a vaccine is considered essential for the effective control of gonorrhoea. The use of outer membrane vesicle vaccines to prevent N. gonorrhoeae infection has garnered considerable interest, and a recent study using a mouse model of experimental gonococcal infections adds support for this approach.
Conflict of interest statement
E.A.S. and K.L.S. hold patents relating to gonococcal vaccine antigens.
Comment on
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Meningococcal Detoxified Outer Membrane Vesicle Vaccines Enhance Gonococcal Clearance in a Murine Infection Model.J Infect Dis. 2022 Feb 15;225(4):650-660. doi: 10.1093/infdis/jiab450. J Infect Dis. 2022. PMID: 34498079 Free PMC article.
References
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- Longtin J, et al. Possible impact of wide-scale vaccination against serogroup B Neisseria meningitidis on gonorrhea incidence rates in one region of Quebec, Canada. Open Forum Infect. Dis. 2017;4:S734–S735. doi: 10.1093/ofid/ofx180.002. - DOI
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