Choline supplementation as an intervention for fetal alcohol spectrum disorders: A commentary
- PMID: 34716714
- PMCID: PMC9529279
- DOI: 10.1111/acer.14732
Choline supplementation as an intervention for fetal alcohol spectrum disorders: A commentary
Comment on
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Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.Alcohol Clin Exp Res. 2021 Sep;45(9):1762-1774. doi: 10.1111/acer.14672. Epub 2021 Aug 18. Alcohol Clin Exp Res. 2021. PMID: 34342017 Free PMC article. Clinical Trial.
References
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- Akison LK, Kuo J, Reid N, Boyd RN, Moritz KM (2018) Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies. Alcohol Clin Exp Res 42:1591–1611. - PubMed
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- Bekdash RA, Zhang C, Sarkar DK (2013) Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in beta-endorphin-producing POMC neurons of the hypothalamus. Alcohol Clin Exp Res 37:1133–1142. - PMC - PubMed
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- Bottom RT, Abbott CW 3rd, Huffman KJ (2020) Rescue of ethanol-induced FASD-like phenotypes via prenatal co-administration of choline. Neuropharmacology 168:107990. - PubMed
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