Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec 28;37(Suppl 2):ii23-ii32.
doi: 10.1093/ndt/gfab262.

Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment

Marion Pépin  1   2 , Ana Carina Ferreira  3   4 , Mustafa Arici  5 , Maie Bachman  6 , Michelangela Barbieri  7 , Inga Arune Bumblyte  8 , Sol Carriazo  9 , Pilar Delgado  10 , Liliana Garneata  11 , Konstantinos Giannakou  12 , Olivier Godefroy  13 , Tomasz Grodzicki  14 , Aleksandra Klimkowicz-Mrowiec  14 , Justina Kurganaite  8 , Sophie Liabeuf  15   16 , Carmen Antonia Mocanu  11 , Giuseppe Paolisso  7   17 , Goce Spasovski  18 , Evgueniy Stefanov Vazelov  19 , Davide Viggiano  20 , Carmine Zoccali  21   22 , Ziad A Massy  1   23 , Andrzej Więcek  24 ; CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target)
Collaborators, Affiliations
Review

Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment

Marion Pépin et al. Nephrol Dial Transplant. .

Erratum in

Abstract

Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify potentially reversible causes of cognitive decline, modify pharmacotherapy, educate the patient and caregiver and provide appropriate patient and caregiver support. Numerous factors are associated with the development and progression of CI in CKD patients and various conditions can influence the results of cognitive assessment in these patients. Here we review clinical warning signs that should lead to cognitive screening; conditions frequent in CKD at risk to interfere with cognitive testing or performance, including specificities of cognitive assessment in dialysis patients or after kidney transplantation; and available tests for screening and observed cognitive patterns in CKD patients.

Keywords: chronic kidney disease; clinical assessment; cognitive impairment; cognitive screening test; comprehensive battery.

PubMed Disclaimer

Figures

Graphical abstract
Graphical abstract
FIGURE 1
FIGURE 1
Integrating CKD in NCDs.
See this image and copyright information in PMC

References

    1. Levey AS, Coresh J. Chronic kidney disease. Lancet 2012; 379: 165–180 - PubMed
    1. Quinn MP, Cardwell CR, Kee F et al. The finding of reduced estimated glomerular filtration rate is associated with increased mortality in a large UK population. Nephrol Dial Transplant 2011; 26: 875–880 - PubMed
    1. Murray AM. Cognitive impairment in the aging dialysis and chronic kidney disease populations: an occult burden. Adv Chronic Kidney Dis 2008; 15: 123–132 - PMC - PubMed
    1. Berger I, Wu S, Masson P et al. Cognition in chronic kidney disease: a systematic review and meta-analysis. BMC Med 2016; 14: 206. - PMC - PubMed
    1. Sachdev PS, Mohan A, Taylor L et al. DSM-5 and mental disorders in older individuals: an overview. Harv Rev Psychiatry 2015; 23: 320–328 - PMC - PubMed

Publication types

MeSH terms