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. 2022 Jul 31;60(4):387-394.
doi: 10.2486/indhealth.2021-0164. Epub 2021 Oct 29.

Longitudinal change in depressive symptoms among healthcare professionals with and without COVID-19 vaccine hesitancy from October 2020 to June 2021 in Japan

Hiroki Asaoka  1 , Yuichi Koido  2 , Yuzuru Kawashima  2 , Miki Ikeda  3 , Yuki Miyamoto  1 , Daisuke Nishi  4   5
Affiliations

Longitudinal change in depressive symptoms among healthcare professionals with and without COVID-19 vaccine hesitancy from October 2020 to June 2021 in Japan

Hiroki Asaoka et al. Ind Health. .

Abstract

This study aimed to compare the longitudinal change in depressive symptoms among healthcare professionals in Japan who are willing to receive novel coronavirus disease (COVID-19) vaccination and those who are unwilling to receive COVID-19 vaccination. The baseline survey was conducted in October 2020 (Survey time 1: T1); respondents in T1 were invited to participate in May 2021 (Survey time 2: T2). Depressive symptoms were assessed by the Patient Health Questionnaire-9 (PHQ-9). Group comparisons of the estimated mean of PHQ-9 score at T1 and T2 were estimated by the analysis of covariance. In T1, 597 participants (response rate: 4.4%) completed all questions. In T2, 211 participants (follow up rate: 35.3%) completed all questions. The group and time interaction effect was significant (F(1, 207)=3.9, p=0.049); depressive symptoms were worse among healthcare professionals who were unwilling to receive vaccination than among those who were willing to receive vaccination. This study showed that depressive symptoms were worse among healthcare professionals who were unwilling to receive COVID-19 vaccination than those who are willing to receive COVID-19 vaccination. This suggests that it is important to take care of healthcare professionals who are unwilling to receive vaccination to prevent mental health deterioration.

Keywords: COVID-19; Depressive symptoms; Healthcare professionals; Vaccination; Vaccine hesitancy.

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Conflict of interest statement

All authors declare no relevant conflicts of interest in relation to the subject of the manuscript.

Figures

Fig. 1.
Fig. 1.
Flowchart of participant recruitment.
Fig. 2.
Fig. 2.
The estimated mean of depressive symptoms at baseline (T1) and T2: analysis of covariance (N=211).
See this image and copyright information in PMC

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