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Review
. 2021 Oct 12:18:408-417.
doi: 10.1016/j.reth.2021.09.009. eCollection 2021 Dec.

Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine

Mason Daniel Hurd  1 , Isha Goel  1 , Yasuyuki Sakai  2 , Yuji Teramura  3   4
Affiliations
Review

Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine

Mason Daniel Hurd et al. Regen Ther. .

Abstract

Ischemic stroke is a major cause of death and disability worldwide and is expected to increase in the future with the aging population. Currently, there are no clinically available treatments for damage sustained during an ischemic stroke, but much research is being conducted in this area. In this review, we will introduce current ischemic stroke treatments along with their limitations, as well as research on potential short and long-term future treatments. There are advantages and disadvantages in these potential treatments, but our understanding of these methods and their effectiveness in clinical trials are improving. We are confident that some future treatments introduced in this review will become commonly used in clinical settings in the future.

Keywords: Exosomes; Ischemic stroke; Regenerative medicine; Stem cells; Treatments.

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Conflict of interest statement

The authors (Mason Daniel Hurd, Isha Goel, Yasuyuki Sakai and Yuji Teramura) declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Outline of current and possible future treatments for stroke therapy.
Fig. 2
Fig. 2
Summary of cell/EVs modification methods being explored for ischemic stroke treatment.
See this image and copyright information in PMC

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