Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Nov 1;106(2):746-749.
doi: 10.4269/ajtmh.21-0875.

Case Report: Rotational Thromboelastometry in Taipan Envenomation

Affiliations
Case Reports

Case Report: Rotational Thromboelastometry in Taipan Envenomation

Catherine L Tacon et al. Am J Trop Med Hyg. .

Abstract

Venom-induced consumption coagulopathy (VICC) is one of the most dangerous syndromes caused by snake envenomation and can be caused by several snake species worldwide, including the Australian coastal taipan. Rotational thromboelastometry (ROTEM) provides real-time point-of-care information on all stages of clot formation; however, it has yet to be formally evaluated in the assessment of VICC. We report three cases of Taipan envenomation causing VICC and the associated ROTEM results. The implications for future use of ROTEM in the assessment, management, and further research of VICC are discussed.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Coagulation pathway with activation from prothrombin activators groups C and D. This figure appears in color at www.ajtmh.org.

References

    1. Johnston CI, Ryan NM, O’Leary MA, Brown SG, Isbister GK, 2017. Australian taipan (Oxyuranus spp.) envenoming: clinical effects and potential benefits of early antivenom therapy - Australian Snakebite Project (ASP-25). Clin Toxicol (Phila) 55: 115–122. - PubMed
    1. Maduwage K, Isbister GK, 2014. Current treatment for venom-induced consumption coagulopathy resulting from snakebite. PLoS Negl Trop Dis 8: e3220. - PMC - PubMed
    1. Isbister GK, Scorgie FE, O’Leary MA, Seldon M, Brown SG, Lincz LF, 2010. Factor deficiencies in venom-induced consumption coagulopathy resulting from Australian elapid envenomation: Australian Snakebite Project (ASP-10). J Thromb Haemostas 8: 2504–2513. - PubMed
    1. Berling I, Isbister GK, 2015. Hematologic effects and complications of snake envenoming. Transfus Med Rev 29: 82–89. - PubMed
    1. Nogami K, 2016. The utility of thromboelastography in inherited and acquired bleeding disorders. Br J Haematol 174: 503–514. - PubMed

Publication types

LinkOut - more resources